Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

126 questions · 132 findings · 17 reviews · Headline outcomes only

No studies found 32 · 24.2%GRADE not reported 2 · 1.5%Very low 23 · 17.4%Low 51 · 38.6%Moderate 24 · 18.2%High 0 · 0%

Interferon vs glatiramer acetate

Number of participants with confirmed progression Risk ratio (M‐H, random, 95% CI) · patients with relapsing‐remitting multiple sclerosis

Interferons showed no clear difference in number of participants with confirmed progression Risk ratio (M‐H,… compared with glatiramer acetate (moderate certainty).

1 finding from 1 review