Findings

What do systematic reviews say?

4 questions · 4 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 1 · 25%High 3 · 75%

Inhaled NO vs control

Mortality before hospital discharge · respiratory failure in preterm infants

Inhaled NO showed no clear difference in death before discharge ‐ Studies with entry before 3 days based on… compared with control (high certainty).

1 finding from 1 review

Inhaled nitric oxide for respiratory failure in preterm infants 2017 · Cochrane Headline outcomes only
RR 1.02 [0.89, 1.18]
10 studies · 1066 participants
High

Inhaled NO vs control

Death or bronchopulmonary dysplasia · respiratory failure in preterm infants

Inhaled NO showed no clear difference in death or bronchopulmonary dysplasia at 36 weeks ‐ Studies with entry… compared with control (high certainty).

1 finding from 1 review

Inhaled nitric oxide for respiratory failure in preterm infants 2017 · Cochrane Headline outcomes only
RR 0.94 [0.87, 1.01]
8 studies · 958 participants
High

Inhaled NO vs control

Intraventricular haemorrhage, Papile grade 3/4 · respiratory failure in preterm infants

Inhaled NO showed no clear difference in intraventricular haemorrhage (grade 3 or 4) ‐ Studies with entry… compared with control (high certainty).

1 finding from 1 review

Inhaled nitric oxide for respiratory failure in preterm infants 2017 · Cochrane Headline outcomes only
RR 1.2 [0.98, 1.47]
6 studies · 773 participants
High

Inhaled NO vs control

Neurodevelopmental disability · respiratory failure in preterm infants

Inhaled NO showed no clear difference in neurodevelopmental disability ‐ Studies with entry before 3 days… compared with control (moderate certainty).

1 finding from 1 review

Inhaled nitric oxide for respiratory failure in preterm infants 2017 · Cochrane Headline outcomes only
RR 1.05 [0.78, 1.4]
2 studies · 208 participants
Moderate