Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

249 questions · 258 findings · 25 reviews

No studies found 52 · 20.2%GRADE not reported 8 · 3.1%Very low 71 · 27.5%Low 56 · 21.7%Moderate 61 · 23.6%High 10 · 3.9%

Inhaled corticosteroids vs placebo

Respiratory exacerbations: number of days on intravenous antibiotics for respiratory exacerbations · adults and children with cystic fibrosis

It is very uncertain whether summary of findings: inhaled corticosteroids changes respiratory exacerbations: number of days on intravenous antibiotics… compared with placebo (very low certainty).

1 finding from 1 review

Inhaled corticosteroids vs no treatment or placebo

Need for nasal continuous positive airway pressure · patients with the management of transient tachypnea of the newborn

It is very uncertain whether inhaled corticosteroids changes need for nasal continuous positive airway pressure compared with no treatment or placebo (very low certainty).

1 finding from 1 review

Inhaled tobramycin (TNS) vs placebo

Eradication of P aeruginosa from the respiratory tract: proportion with positive respiratory culture for P aeruginosa · adults and children with cystic fibrosis and a positive microbiological isolate of P aeruginosa from a respiratory tract specimen

Inhaled tobramycin (TNS) may leads to lower eradication of P aeruginosa from the respiratory tract: proportion… compared with placebo (low certainty).

1 finding from 1 review