Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

11 questions · 15 findings · 2 reviews

No studies found 4 · 26.7%GRADE not reported 0 · 0%Very low 1 · 6.7%Low 8 · 53.3%Moderate 2 · 13.3%High 0 · 0%

IUI in a natural cycle vs TI or expectant management

Pregnancy rate per couple (all cycles) · participants with unexplained subfertility

IUI in a natural cycle probably leads to higher pregnancy rate per couple (all cycles) compared with TI or expectant management (moderate certainty).

2 findings from 1 review

IUI in a natural cycle vs TI or expectant management

Multiple pregnancy rate · participants with unexplained subfertility

IUI in a natural cycle showed no clear difference in multiple pregnancy rate per couple compared with TI or expectant management (low certainty).

2 findings from 1 review

IUI in a natural cycle vs TI or expectant management

Ovarian Hyperstimulation Syndrome rate per woman ‐ not reported · participants with unexplained subfertility

The review found no eligible studies for this question.

2 findings from 1 review

IUI in a natural cycle vs TI or expectant management

Ectopic pregnancy rate per couple · participants with unexplained subfertility

IUI in a natural cycle showed no clear difference in ectopic pregnancy rate per couple compared with TI or expectant management (low certainty).

2 findings from 1 review