Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

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26 questions · 26 findings · 2 reviews · Developmental, Psychosocial and Learning Problems

No studies found 0 · 0%GRADE not reported 6 · 23.1%Very low 3 · 11.5%Low 13 · 50%Moderate 4 · 15.4%High 0 · 0%

Intermittent vs any daily iron supplementation

Iron deficiency (using ferritin concentrations) · children under 12 years of age

It is very uncertain whether intermittent changes iron deficiency (using ferritin concentrations) compared with daily use of iron supplements (very low certainty).

1 finding from 1 review

Intermittent use of iron supplements vs any daily iron supplementation

Iron deficiency (as defined by trialists) · adolescent and adult menstruating women

It is very uncertain whether intermittent iron supplementation changes iron deficiency (as defined by the trialists using indicators of… compared with daily iron supplementation (very low certainty).

1 finding from 1 review

Intermittent use of iron supplements vs any daily iron supplementation

Side effects or other adverse events · adolescent and adult menstruating women

Intermittent iron supplementation may leads to lower any adverse side effects compared with daily iron supplementation (low certainty).

1 finding from 1 review

Intermittent use of iron supplements vs any daily iron supplementation

Anaemia · adolescent and adult menstruating women

Intermittent iron supplementation showed no clear difference in anaemia (haemoglobin concentration below a cut‐off defined by the… compared with daily iron supplementation (moderate certainty).

1 finding from 1 review

Intermittent use of iron supplements vs placebo or no intervention

Anaemia · children under 12 years of age

Intermittent use of iron supplements probably leads to lower anaemia (haemoglobin below a cut‐off defined by trialists, taking… compared with placebo or no intervention (moderate certainty).

1 finding from 1 review

Intermittent use of iron supplements vs placebo or no intervention

Iron deficiency (using ferritin concentrations) · children under 12 years of age

It is very uncertain whether intermittent use of iron supplements changes iron deficiency (using ferritin concentrations) compared with placebo or no intervention (very low certainty).

1 finding from 1 review

Intermittent use of iron supplements vs placebo or no intervention

Iron status (ferritin concentrations in ng/mL) · children under 12 years of age

Intermittent use of iron supplements may leads to higher iron status (ferritin (μg/L) compared with placebo or no intervention (low certainty).

1 finding from 1 review

Intermittent iron supplementation (alone or with any other micronutrients) vs no supplementation or placebo

Anaemia · adolescent and adult menstruating women

Intermittent iron supplementation (alone or with any other… may leads to lower anaemia (haemoglobin concentration below a cut‐off defined by the… compared with no supplementation or placebo (low certainty).

1 finding from 1 review