What do systematic reviews say?

Hypofractionated radiotherapy vs radiotherapy

The review found no eligible studies for this question.

• Radiotherapy for diffuse brainstem glioma in children and young adults 2016 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Hypofractionated radiotherapy vs radiotherapy

The review found no eligible studies for this question.

• Radiotherapy for diffuse brainstem glioma in children and young adults 2016 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Hypofractionated radiotherapy vs radiotherapy

The review found no eligible studies for this question.

• Radiotherapy for diffuse brainstem glioma in children and young adults 2016 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Hypofractionated radiotherapy vs radiotherapy

The review found no eligible studies for this question.

• Radiotherapy for diffuse brainstem glioma in children and young adults 2016 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Hypofractionated radiotherapy vs radiotherapy

• Radiotherapy for diffuse brainstem glioma in children and young adults 2016 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 71 participants
  Low

Hypofractionated radiotherapy vs radiotherapy

Hypofractionated radiotherapy showed no clear difference in overall survival compared with conventional radiotherapy (moderate certainty).

• Radiotherapy for diffuse brainstem glioma in children and young adults 2016 · Cochrane Headline outcomes only
  HR 1.03 [0.53, 2.01]
  1 study · 71 participants
  Moderate

Hypofractionated radiotherapy vs radiotherapy

Hypofractionated radiotherapy showed no clear difference in progression‐free survival compared with conventional radiotherapy (low certainty).

• Radiotherapy for diffuse brainstem glioma in children and young adults 2016 · Cochrane Headline outcomes only
  HR 1.19 [0.63, 2.22]
  1 study · 71 participants
  Low

Hypofractionated radiotherapy vs daily conventionally fractionated radiotherapy

It is very uncertain whether hypofractionated radiotherapy changes overall survival compared with daily conventionally fractionated radiotherapy (very low certainty).

• External beam radiation dose escalation for high grade glioma 2020 · Cochrane Headline outcomes only
  HR 0.95 [0.78, 1.17]
  5 studies · 943 participants
  Very low

Hypofractionated radiotherapy vs daily conventionally fractionated radiotherapy

• External beam radiation dose escalation for high grade glioma 2020 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 848 participants
  GRADE not reported

Hypofractionated radiotherapy vs daily conventionally fractionated radiotherapy

• External beam radiation dose escalation for high grade glioma 2020 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

Hypofractionated radiotherapy vs daily conventionally fractionated radiotherapy

• External beam radiation dose escalation for high grade glioma 2020 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 361 participants
  GRADE not reported

Hypofractionated radiotherapy vs daily conventionally fractionated radiotherapy

Hypofractionated radiotherapy showed no clear difference in overall survival for subgroup aged ≥ 60 years glioblastoma compared with daily conventionally fractionated radiotherapy (high certainty).

• External beam radiation dose escalation for high grade glioma 2020 · Cochrane Headline outcomes only
  HR 1.16 [0.92, 1.46]
  2 studies · 293 participants
  High