Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

22 questions · 22 findings · 2 reviews

No studies found 10 · 45.5%GRADE not reported 0 · 0%Very low 12 · 54.5%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Closest answers

The findings closest to your search, judged one by one by TypeSafe's Jev model.

  • Direct match · question page
    • Oral hydromorphone vs placebo · Moderate benefit: ≥ 30% reduction in pain PGIC much or very much improved
      Hydromorphone for neuropathic pain in adults 2016 · Cochrane Headline outcomes only
      no estimate extracted
      Studies not reported
      No studies found
  • Direct match · question page
    • Hydromorphone vs oxycodone · Participant‐reported pain relief
      Hydromorphone for cancer pain 2021 · Cochrane Headline outcomes only
      no estimate extracted
      Studies not reported
      No studies found
  • Direct match · question page
    • Hydromorphone vs oxycodone · Participant‐reported pain intensity (as measured by VAS or BPI)
      Hydromorphone for cancer pain 2021 · Cochrane Headline outcomes only
      no estimate extracted
      4 studies · 462 participants
      Very low
  • Direct match · question page
    • Hydromorphone vs fentanyl · Participant‐reported pain intensity (as measured by NRS)
      Hydromorphone for cancer pain 2021 · Cochrane Headline outcomes only
      no estimate extracted
      1 study · 82 participants
      Very low
  • Related · question page
    • Hydromorphone vs morphine · Specific adverse events – vomiting
      Hydromorphone for cancer pain 2021 · Cochrane Headline outcomes only
      RR 0.87 [0.58, 1.31]
      1 study · 200 participants
      Very low

Oral hydromorphone vs placebo

Moderate benefit: At least 30% reduction in pain, or PGIC much or very much improved · adults with chronic neuropathic pain

The review found no eligible studies for this question.

1 finding from 1 review

Hydromorphone vs oxycodone

Participant‐reported pain intensity VAS (0‐10, lower score = less pain) · people with moderate to severe cancer pain
1 finding from 1 review

Hydromorphone vs morphine

Nausea · people with moderate to severe cancer pain

It is very uncertain whether hydromorphone changes specific adverse events – nausea compared with morphine (very low certainty).

1 finding from 1 review

Hydromorphone vs morphine

Vomiting · people with moderate to severe cancer pain

It is very uncertain whether hydromorphone changes specific adverse events – vomiting compared with morphine (very low certainty).

1 finding from 1 review

Hydromorphone vs morphine

Dizziness · people with moderate to severe cancer pain

It is very uncertain whether hydromorphone changes specific adverse events – dizziness compared with morphine (very low certainty).

1 finding from 1 review

Hydromorphone vs morphine

Quality of life · people with moderate to severe cancer pain

The review found no eligible studies for this question.

1 finding from 1 review

Hydromorphone vs fentanyl

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · people with moderate to severe cancer pain
1 finding from 1 review

Hydromorphone vs fentanyl

Relief of pain · people with moderate to severe cancer pain

The review found no eligible studies for this question.

1 finding from 1 review

Hydromorphone vs fentanyl

Nausea · people with moderate to severe cancer pain

The review found no eligible studies for this question.

1 finding from 1 review

Hydromorphone vs fentanyl

Vomiting · people with moderate to severe cancer pain

The review found no eligible studies for this question.

1 finding from 1 review

Hydromorphone vs fentanyl

Dizziness · people with moderate to severe cancer pain

The review found no eligible studies for this question.

1 finding from 1 review

Hydromorphone vs oxycodone

Relief of pain · people with moderate to severe cancer pain

The review found no eligible studies for this question.

1 finding from 1 review

Hydromorphone vs fentanyl

Constipation · people with moderate to severe cancer pain

The review found no eligible studies for this question.

1 finding from 1 review

Hydromorphone vs fentanyl

Quality of life · people with moderate to severe cancer pain

The review found no eligible studies for this question.

1 finding from 1 review

Hydromorphone vs oxycodone

Nausea · people with moderate to severe cancer pain

It is very uncertain whether hydromorphone changes specific adverse events – nausea compared with oxycodone (very low certainty).

1 finding from 1 review

Hydromorphone vs oxycodone

Vomiting · people with moderate to severe cancer pain

It is very uncertain whether hydromorphone changes specific adverse events – vomiting compared with oxycodone (very low certainty).

1 finding from 1 review

Hydromorphone vs oxycodone

Dizziness · people with moderate to severe cancer pain

It is very uncertain whether hydromorphone changes specific adverse events – dizziness compared with oxycodone (very low certainty).

1 finding from 1 review

Hydromorphone vs oxycodone

Constipation · people with moderate to severe cancer pain

It is very uncertain whether hydromorphone changes specific adverse events – constipation compared with oxycodone (very low certainty).

1 finding from 1 review

Hydromorphone vs oxycodone

Quality of life · people with moderate to severe cancer pain

The review found no eligible studies for this question.

1 finding from 1 review