Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

27 questions · 27 findings · 2 reviews · Pain, Palliative and Supportive Care

No studies found 13 · 48.1%GRADE not reported 0 · 0%Very low 14 · 51.9%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Hydromorphone vs oxycodone

Participant‐reported pain intensity VAS (0‐10, lower score = less pain) · people with moderate to severe cancer pain
1 finding from 1 review

Hydromorphone vs morphine

Nausea · people with moderate to severe cancer pain

It is very uncertain whether hydromorphone changes specific adverse events – nausea compared with morphine (very low certainty).

1 finding from 1 review

Hydromorphone vs morphine

Vomiting · people with moderate to severe cancer pain

It is very uncertain whether hydromorphone changes specific adverse events – vomiting compared with morphine (very low certainty).

1 finding from 1 review

Hydromorphone vs morphine

Dizziness · people with moderate to severe cancer pain

It is very uncertain whether hydromorphone changes specific adverse events – dizziness compared with morphine (very low certainty).

1 finding from 1 review

Hydromorphone vs morphine

Quality of life · people with moderate to severe cancer pain

The review found no eligible studies for this question.

1 finding from 1 review

Hydromorphone vs fentanyl

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · people with moderate to severe cancer pain
1 finding from 1 review

Hydromorphone vs fentanyl

Relief of pain · people with moderate to severe cancer pain

The review found no eligible studies for this question.

1 finding from 1 review

Hydromorphone vs fentanyl

Nausea · people with moderate to severe cancer pain

The review found no eligible studies for this question.

1 finding from 1 review

Hydromorphone vs fentanyl

Vomiting · people with moderate to severe cancer pain

The review found no eligible studies for this question.

1 finding from 1 review

Hydromorphone vs fentanyl

Dizziness · people with moderate to severe cancer pain

The review found no eligible studies for this question.

1 finding from 1 review

Hydromorphone vs oxycodone

Relief of pain · people with moderate to severe cancer pain

The review found no eligible studies for this question.

1 finding from 1 review

Hydromorphone vs fentanyl

Constipation · people with moderate to severe cancer pain

The review found no eligible studies for this question.

1 finding from 1 review

Hydromorphone vs fentanyl

Quality of life · people with moderate to severe cancer pain

The review found no eligible studies for this question.

1 finding from 1 review

Hydromorphone vs oxycodone

Nausea · people with moderate to severe cancer pain

It is very uncertain whether hydromorphone changes specific adverse events – nausea compared with oxycodone (very low certainty).

1 finding from 1 review

Hydromorphone vs oxycodone

Vomiting · people with moderate to severe cancer pain

It is very uncertain whether hydromorphone changes specific adverse events – vomiting compared with oxycodone (very low certainty).

1 finding from 1 review

Hydromorphone vs oxycodone

Dizziness · people with moderate to severe cancer pain

It is very uncertain whether hydromorphone changes specific adverse events – dizziness compared with oxycodone (very low certainty).

1 finding from 1 review

Hydromorphone vs oxycodone

Constipation · people with moderate to severe cancer pain

It is very uncertain whether hydromorphone changes specific adverse events – constipation compared with oxycodone (very low certainty).

1 finding from 1 review

Hydromorphone vs oxycodone

Quality of life · people with moderate to severe cancer pain

The review found no eligible studies for this question.

1 finding from 1 review

Hydromorphone vs morphine

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · people with moderate to severe cancer pain
1 finding from 1 review