Findings

What do systematic reviews say?

28 questions · 28 findings · 2 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 15 · 53.6%Low 5 · 17.9%Moderate 7 · 25%High 1 · 3.6%

Asthma ‐ Infancy (incidence) · infants

Higher showed no clear difference in asthma ‐ infant incidence compared with lower PUFA intake (low certainty).

1 finding from 1 review

Polyunsaturated fatty acid supplementation in infancy for the prevention of allergy 2016 · Cochrane Headline outcomes only
RR 1.04 [0.8, 1.35]
3 studies · 1162 participants
Low

Eczema ‐ Infancy (incidence) · infants

It is very uncertain whether higher changes dermatitis/eczema ‐ infant incidence compared with lower PUFA intake (very low certainty).

1 finding from 1 review

Polyunsaturated fatty acid supplementation in infancy for the prevention of allergy 2016 · Cochrane Headline outcomes only
RR 0.93 [0.82, 1.06]
7 studies · 1906 participants
Very low

Allergic rhinitis ‐ infant incidence · infants

It is very uncertain whether higher changes allergic rhinitis ‐ infant incidence compared with lower PUFA intake (very low certainty).

1 finding from 1 review

Polyunsaturated fatty acid supplementation in infancy for the prevention of allergy 2016 · Cochrane Headline outcomes only
RR 0.47 [0.23, 0.96]
2 studies · 594 participants
Very low

Food allergy ‐ Infancy (incidence) · infants

It is very uncertain whether higher changes food allergy ‐ infant incidence compared with lower PUFA intake (very low certainty).

1 finding from 1 review

Polyunsaturated fatty acid supplementation in infancy for the prevention of allergy 2016 · Cochrane Headline outcomes only
RR 0.81 [0.56, 1.19]
3 studies · 915 participants
Very low

All allergic disease ‐ childhood (incidence) · infants

It is very uncertain whether higher changes all allergic disease ‐ childhood incidence compared with lower PUFA intake (very low certainty).

1 finding from 1 review

Polyunsaturated fatty acid supplementation in infancy for the prevention of allergy 2016 · Cochrane Headline outcomes only
RR 0.69 [0.47, 1.02]
2 studies · 154 participants
Very low

Asthma ‐ childhood (incidence) · infants

It is very uncertain whether higher changes asthma ‐ childhood incidence compared with lower PUFA intake (very low certainty).

1 finding from 1 review

Polyunsaturated fatty acid supplementation in infancy for the prevention of allergy 2016 · Cochrane Headline outcomes only
RR 0.45 [0.2, 1.02]
1 study · 89 participants
Very low

Eczema ‐ childhood (incidence) · infants

It is very uncertain whether higher changes dermatitis/eczema ‐ childhood incidence compared with lower PUFA intake (very low certainty).

1 finding from 1 review

Polyunsaturated fatty acid supplementation in infancy for the prevention of allergy 2016 · Cochrane Headline outcomes only
RR 0.65 [0.34, 1.24]
2 studies · 154 participants
Very low

Food allergy ‐ childhood (incidence) · infants

It is very uncertain whether higher changes food allergy ‐ childhood incidence compared with lower PUFA intake (very low certainty).

1 finding from 1 review

Polyunsaturated fatty acid supplementation in infancy for the prevention of allergy 2016 · Cochrane Headline outcomes only
RR 2.27 [0.25, 20.68]
1 study · 65 participants
Very low