What do systematic reviews say?

Higher‐dose heparin vs standard‐dose heparin

Higher‐dose heparin showed no clear difference in VTE compared with standard‐dose heparin (low certainty).

• Pharmacological interventions for preventing venous thromboembolism in people undergoing bariatric surgery 2022 · Cochrane Headline outcomes only
  RR 0.55 [0.05, 5.99]
  4 studies · 597 participants
  Low

Higher‐dose heparin vs standard‐dose heparin

Higher‐dose heparin showed no clear difference in major bleeding compared with standard‐dose heparin (low certainty).

• Pharmacological interventions for preventing venous thromboembolism in people undergoing bariatric surgery 2022 · Cochrane Headline outcomes only
  RR 1.19 [0.48, 2.96]
  4 studies · 597 participants
  Low

Higher‐dose heparin vs standard‐dose heparin

• Pharmacological interventions for preventing venous thromboembolism in people undergoing bariatric surgery 2022 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 597 participants
  Low

Higher‐dose heparin vs standard‐dose heparin

• Pharmacological interventions for preventing venous thromboembolism in people undergoing bariatric surgery 2022 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 597 participants
  Low

Higher‐dose heparin vs standard‐dose heparin

It is very uncertain whether higher‐dose heparin changes PE compared with standard‐dose heparin (very low certainty).

• Pharmacological interventions for preventing venous thromboembolism in people undergoing bariatric surgery 2022 · Cochrane Headline outcomes only
  RR 0.37 [0.02, 8.92]
  2 studies · 310 participants
  Very low

Higher‐dose heparin vs standard‐dose heparin

It is very uncertain whether higher‐dose heparin changes DVT compared with standard‐dose heparin (very low certainty).

• Pharmacological interventions for preventing venous thromboembolism in people undergoing bariatric surgery 2022 · Cochrane Headline outcomes only
  RR 1.1 [0.07, 17.4]
  4 studies · 597 participants
  Very low

Higher‐dose heparin vs standard‐dose heparin

It is very uncertain whether higher‐dose heparin changes adverse events (thrombocytopenia) compared with standard‐dose heparin (very low certainty).

• Pharmacological interventions for preventing venous thromboembolism in people undergoing bariatric surgery 2022 · Cochrane Headline outcomes only
  RR 1.1 [0.07, 17.4]
  2 studies · 310 participants
  Very low