Findings

What do systematic reviews say?

6 questions · 6 findings · 5 reviews

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No studies found 4 · 66.7%GRADE not reported 2 · 33.3%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

High‐dose vs low‐dose rFVIIa

Quality of life · adults and children with hemophilia A or B with inhibitors

The review found no eligible studies for this question.

1 finding from 1 review

Bypassing agent prophylaxis in people with hemophilia A or B with inhibitors 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

High‐dose vs low‐dose coenzyme Q10 and vitamin E

Longer‐term (minimum 1 month) change in generic quality of life scores · people with speech disorder resulting from hereditary ataxias

1 finding from 1 review

Treatment for speech disorder in Friedreich ataxia and other hereditary ataxia syndromes 2014 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

High‐dose vs low‐dose coenzyme Q10 and vitamin E

Short‐term (within 1 month) change in quality of life scores related to communication as measured by validated communication assessments · people with speech disorder resulting from hereditary ataxias

1 finding from 1 review

Treatment for speech disorder in Friedreich ataxia and other hereditary ataxia syndromes 2014 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

ASA + high‐dose LMWH vs ASA + low‐dose LMWH or UFH

Quality of life · people with antiphospholipid antibodies and no history of thrombosis

The review found no eligible studies for this question.

1 finding from 1 review

Antiplatelet and anticoagulant agents for primary prevention of thrombosis in individuals with antiphospholipid… 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

High‐dose corticosteroids vs moderate‐dose or no corticosteroids

Quality of life · adults with metastatic extradural spinal cord compression (without peptic ulceration or infection; mixed prognosis)

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for the treatment of metastatic extradural spinal cord compression in adults 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Prophylactic platelet transfusions with high‐dose schedule vs standard‐dose strategies

Quality of life ‐ not reported · People with a haematological disorder

The review found no eligible studies for this question.

1 finding from 1 review

Different doses of prophylactic platelet transfusion for preventing bleeding in people with haematological disorders… 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found