Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

283 questions · 299 findings · 27 reviews

No studies found 74 · 24.7%GRADE not reported 27 · 9%Very low 77 · 25.8%Low 82 · 27.4%Moderate 28 · 9.4%High 11 · 3.7%

Heparin plus aspirin vs aspirin

Adverse events in the mother ‐ Bleeding · women with persistent antiphospholipid antibodies and recurrent pregnancy loss

Heparin plus aspirin showed no clear difference in adverse events in the mother ‐ Bleeding compared with aspirin (low certainty).

1 finding from 1 review

Heparin plus aspirin vs aspirin

Preterm delivery of a live infant · women with persistent antiphospholipid antibodies and recurrent pregnancy loss

It is very uncertain whether heparin plus aspirin changes preterm delivery of a live infant compared with aspirin (very low certainty).

1 finding from 1 review

Heparin plus aspirin vs aspirin

Intrauterine growth restriction · women with persistent antiphospholipid antibodies and recurrent pregnancy loss

It is very uncertain whether heparin plus aspirin changes intrauterine growth restriction compared with aspirin (very low certainty).

1 finding from 1 review