Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

263 questions · 270 findings · 9 reviews

No studies found 85 · 31.5%GRADE not reported 24 · 8.9%Very low 85 · 31.5%Low 42 · 15.6%Moderate 21 · 7.8%High 13 · 4.8%

HALOPERIDOL vs OLANZAPINE

Specific behaviour ‐ threat or injury to self or others average change score (ABS, high = worse) at 2 hours · psychosis‐induced aggression or agitation

It is very uncertain whether HALOPERIDOL changes specific behaviour ‐ threat or injury to self or others compared with OTHER ANTIPSYCHOTIC: e. OLANZAPINE (very low certainty).

1 finding from 1 review

HALOPERIDOL vs OLANZAPINE

Global outcome ‐ need for benzodiazepine during 24 hours · psychosis‐induced aggression or agitation

It is very uncertain whether HALOPERIDOL changes global outcome ‐ need for benzodiazepine during 24 hours compared with OTHER ANTIPSYCHOTIC: e. OLANZAPINE (very low certainty).

1 finding from 1 review

HALOPERIDOL vs OLANZAPINE

Adverse effects: Specific ‐ dystonia during 24 hours · psychosis‐induced aggression or agitation

It is very uncertain whether HALOPERIDOL changes adverse effects: Specific ‐ dystonia during 24 hours compared with OTHER ANTIPSYCHOTIC: e. OLANZAPINE (very low certainty).

1 finding from 1 review

HALOPERIDOL vs OTHER ANTIPSYCHOTIC: f. PERPHENAZINE

Global outcome: general ‐ no improvement · patients with psychosis‐induced aggression or agitation

It is very uncertain whether HALOPERIDOL changes global outcome: general ‐ no improvement compared with OTHER ANTIPSYCHOTIC: f. PERPHENAZINE (very low certainty).

1 finding from 1 review

HALOPERIDOL vs OTHER ANTIPSYCHOTIC: f. PERPHENAZINE

Adverse effect: Specific ‐ hypotensive episode · patients with psychosis‐induced aggression or agitation

It is very uncertain whether HALOPERIDOL changes adverse effect: Specific ‐ hypotensive episode compared with OTHER ANTIPSYCHOTIC: f. PERPHENAZINE (very low certainty).

1 finding from 1 review

HALOPERIDOL vs OTHER ANTIPSYCHOTIC: f. PERPHENAZINE

Adverse effect ‐ discontinued due to EPS · patients with psychosis‐induced aggression or agitation

It is very uncertain whether HALOPERIDOL changes adverse effect ‐ discontinued due to EPS compared with OTHER ANTIPSYCHOTIC: f. PERPHENAZINE (very low certainty).

1 finding from 1 review