Findings

What do systematic reviews say?

7 questions · 7 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 2 · 28.6%Very low 0 · 0%Low 3 · 42.9%Moderate 0 · 0%High 2 · 28.6%

HALOPERIDOL + PROMETHAZINE vs OLANZAPINE

Adverse effects: Specific and serious adverse effect ‐ by 24 hours Central nervous system ‐ excessive sedation · people with psychosis‐induced aggression

HALOPERIDOL + PROMETHAZINE showed no clear difference in adverse effects: Specific and serious adverse effects by 24 hours… compared with ANTIPSYCHOTIC ‐ OLANZAPINE (low certainty).

1 finding from 1 review

Haloperidol plus promethazine for psychosis‐induced aggression 2016 · Cochrane Headline outcomes only
RR 0.67 [0.12, 3.84]
2 studies · 116 participants
Low

HALOPERIDOL + PROMETHAZINE vs OLANZAPINE

Adverse effect: Specific ‐ Death · people with psychosis‐induced aggression

1 finding from 1 review

Haloperidol plus promethazine for psychosis‐induced aggression 2016 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

HALOPERIDOL + PROMETHAZINE vs OLANZAPINE

Service outcomes: Not discharged ‐ by 4 hours · people with psychosis‐induced aggression

HALOPERIDOL + PROMETHAZINE showed no clear difference in service outcomes: Not discharged ‐ by 4 hours compared with ANTIPSYCHOTIC ‐ OLANZAPINE (high certainty).

1 finding from 1 review

Haloperidol plus promethazine for psychosis‐induced aggression 2016 · Cochrane Headline outcomes only
RR 0.94 [0.77, 1.16]
1 study · 300 participants
High

HALOPERIDOL + PROMETHAZINE vs OLANZAPINE

Aggression · people with psychosis‐induced aggression

1 finding from 1 review

Haloperidol plus promethazine for psychosis‐induced aggression 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 60 participants
Low

HALOPERIDOL + PROMETHAZINE vs OLANZAPINE

Economic outcomes: Cost of care · people with psychosis‐induced aggression

1 finding from 1 review

Haloperidol plus promethazine for psychosis‐induced aggression 2016 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

HALOPERIDOL + PROMETHAZINE vs OLANZAPINE

Tranquil or asleep: Not tranquil or asleep ‐ by 30 mins · people with psychosis‐induced aggression

HALOPERIDOL + PROMETHAZINE showed no clear difference in tranquil or asleep: Not tranquil or asleep ‐ by 30 mins compared with ANTIPSYCHOTIC ‐ OLANZAPINE (high certainty).

1 finding from 1 review

Haloperidol plus promethazine for psychosis‐induced aggression 2016 · Cochrane Headline outcomes only
RR 0.6 [0.22, 1.61]
1 study · 300 participants
High

HALOPERIDOL + PROMETHAZINE vs OLANZAPINE

Global state: Needing restraints or seclusion ‐ by 12 hours · people with psychosis‐induced aggression

HALOPERIDOL + PROMETHAZINE showed no clear difference in global state: Needing restraints or seclusion by 12 hours compared with ANTIPSYCHOTIC ‐ OLANZAPINE (low certainty).

1 finding from 1 review

Haloperidol plus promethazine for psychosis‐induced aggression 2016 · Cochrane Headline outcomes only
RR 5 [0.62, 40.28]
1 study · 60 participants
Low