Findings

What do systematic reviews say?

2 questions · 2 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 2 · 100%High 0 · 0%

HALOPERIDOL + PROMETHAZINE vs midazolam

Global outcome ‐ need for restraint or seclusion · people with psychosis‐induced aggression

HALOPERIDOL + PROMETHAZINE showed no clear difference in global state: Needing restraints or seclusion‐ by 2 hours compared with BENZODIAZEPINES ‐ MIDAZOLAM (moderate certainty).

1 finding from 1 review

Haloperidol plus promethazine for psychosis‐induced aggression 2016 · Cochrane Headline outcomes only
RR 1.22 [0.82, 1.82]
1 study · 301 participants
Moderate

HALOPERIDOL + PROMETHAZINE vs lorazepam

Global state: Needing restraints or seclusion ‐ by 12 hours · people with psychosis‐induced aggression

HALOPERIDOL + PROMETHAZINE showed no clear difference in global state: Needing restraints or seclusion ‐ by 12 hours compared with BENZODIAZEPINES ‐ LORAZEPAM (moderate certainty).

1 finding from 1 review

Haloperidol plus promethazine for psychosis‐induced aggression 2016 · Cochrane Headline outcomes only
RR 0.82 [0.35, 1.89]
1 study · 200 participants
Moderate