Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

23 questions · 24 findings · 3 reviews

No studies found 7 · 29.2%GRADE not reported 2 · 8.3%Very low 10 · 41.7%Low 3 · 12.5%Moderate 0 · 0%High 2 · 8.3%

HALOPERIDOL vs OLANZAPINE

Specific behaviour ‐ threat or injury to self or others average change score (ABS, high = worse) at 2 hours · psychosis‐induced aggression or agitation

It is very uncertain whether HALOPERIDOL changes specific behaviour ‐ threat or injury to self or others compared with OTHER ANTIPSYCHOTIC: e. OLANZAPINE (very low certainty).

1 finding from 1 review

HALOPERIDOL vs OLANZAPINE

Global outcome ‐ need for benzodiazepine during 24 hours · psychosis‐induced aggression or agitation

It is very uncertain whether HALOPERIDOL changes global outcome ‐ need for benzodiazepine during 24 hours compared with OTHER ANTIPSYCHOTIC: e. OLANZAPINE (very low certainty).

1 finding from 1 review

HALOPERIDOL vs OLANZAPINE

Adverse effects: Specific ‐ dystonia during 24 hours · psychosis‐induced aggression or agitation

It is very uncertain whether HALOPERIDOL changes adverse effects: Specific ‐ dystonia during 24 hours compared with OTHER ANTIPSYCHOTIC: e. OLANZAPINE (very low certainty).

1 finding from 1 review

HALOPERIDOL + PROMETHAZINE vs OLANZAPINE

Adverse effects: Specific and serious adverse effect ‐ by 24 hours Central nervous system ‐ excessive sedation · people with psychosis‐induced aggression

HALOPERIDOL + PROMETHAZINE showed no clear difference in adverse effects: Specific and serious adverse effects by 24 hours… compared with ANTIPSYCHOTIC ‐ OLANZAPINE (low certainty).

1 finding from 1 review

HALOPERIDOL vs OLANZAPINE

Symptoms of delirium within 24 hoursa · terminally ill adults with delirium

It is very uncertain whether summary of findings: haloperidol changes symptoms of delirium within 24 hoursa compared with olanzapine (very low certainty).

1 finding from 1 review