Findings

What do systematic reviews say?

6 questions · 6 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 6 · 100%High 0 · 0%

GnRH antagonist vs long‐course GnRH agonist

Live birth rate per woman · women undergoing assisted reproductive technology (ART)

GnRH antagonist showed no clear difference in live birth rate per woman randomised compared with long‐course GnRH agonist (moderate certainty).

1 finding from 1 review

Gonadotrophin‐releasing hormone antagonists for assisted reproductive technology 2016 · Cochrane Headline outcomes only
OR 1.02 [0.85, 1.23]
12 studies · 2303 participants
Moderate

GnRH antagonist vs long‐course GnRH agonist

OHSS per woman randomised (any grade) · women undergoing assisted reproductive technology (ART)

GnRH antagonist probably leads to lower OHSS per woman randomised (any grade) compared with long‐course GnRH agonist (moderate certainty).

1 finding from 1 review

Gonadotrophin‐releasing hormone antagonists for assisted reproductive technology 2016 · Cochrane Headline outcomes only
OR 0.61 [0.51, 0.72]
36 studies · 7944 participants
Moderate

GnRH antagonist vs long‐course GnRH agonist

Ongoing pregnancy · women undergoing assisted reproductive technology (ART)

GnRH antagonist showed no clear difference in ongoing pregnancy rate per woman randomised compared with long‐course GnRH agonist (moderate certainty).

1 finding from 1 review

Gonadotrophin‐releasing hormone antagonists for assisted reproductive technology 2016 · Cochrane Headline outcomes only
OR 0.92 [0.83, 1.01]
37 studies · 8311 participants
Moderate

GnRH antagonist vs long‐course GnRH agonist

Clinical pregnancy rate · women undergoing assisted reproductive technology (ART)

GnRH antagonist showed no clear difference in clinical pregnancy rate per woman randomised compared with long‐course GnRH agonist (moderate certainty).

1 finding from 1 review

Gonadotrophin‐releasing hormone antagonists for assisted reproductive technology 2016 · Cochrane Headline outcomes only
OR 0.91 [0.83, 1]
54 studies · 9959 participants
Moderate

GnRH antagonist vs long‐course GnRH agonist

Miscarriage · women undergoing assisted reproductive technology (ART)

GnRH antagonist showed no clear difference in miscarriage rate per woman randomised compared with long‐course GnRH agonist (moderate certainty).

1 finding from 1 review

Gonadotrophin‐releasing hormone antagonists for assisted reproductive technology 2016 · Cochrane Headline outcomes only
OR 1.03 [0.82, 1.29]
34 studies · 7082 participants
Moderate

GnRH antagonist vs long‐course GnRH agonist

Cycle cancellation due to poor ovarian response · women undergoing assisted reproductive technology (ART)

GnRH antagonist probably leads to higher cycle cancellation due to poor ovarian response compared with long‐course GnRH agonist (moderate certainty).

1 finding from 1 review

Gonadotrophin‐releasing hormone antagonists for assisted reproductive technology 2016 · Cochrane Headline outcomes only
OR 1.32 [1.06, 1.65]
25 studies · 5230 participants
Moderate