Findings

What do systematic reviews say?

26 questions · 26 findings · 5 reviews

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No studies found 3 · 11.5%GRADE not reported 4 · 15.4%Very low 3 · 11.5%Low 13 · 50%Moderate 2 · 7.7%High 1 · 3.8%

Fibrin glue instillation under skin flaps vs no‐fibrin

PostoperativecomplicationsRR · people with breast and axillary surgery

Fibrin glue instillation under skin flaps showed no clear difference in postoperativecomplicationsRR compared with no‐fibrin (low certainty).

1 finding from 1 review

Fibrin glue instillation under skin flaps to prevent seroma‐related morbidity following breast and axillary surgery 2013 · Cochrane Headline outcomes only
RR 1.13 [0.63, 2.04]
11 studies · 981 participants
Low

Fibrin glue instillation under skin flaps vs no‐fibrin

Length of hospital stay (theoretical) · people with breast and axillary surgery

1 finding from 1 review

Fibrin glue instillation under skin flaps to prevent seroma‐related morbidity following breast and axillary surgery 2013 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 364 participants
Low

Traditional iliac bone graft plus fibrin glue vs Traditional iliac bone graft alone

Radiographic assessment: coronal bone volume (cm3) · Patients aged 7 to 16 years with unilateral or bilateral cleft lip and palate (alveolar cleft)

Traditional iliac bone graft plus fibrin glue led to higher radiographic assessment: coronal bone volume (cm3) compared with traditional iliac bone graft alone; GRADE not reported.

1 finding from 1 review

Secondary bone grafting for alveolar cleft in children with cleft lip or cleft lip and palate 2011 · Cochrane All outcomes
At least 3 months
MD 42.62 [20.99, 64.25]
1 study · 27 participants
GRADE not reported

Traditional iliac bone graft plus fibrin glue vs Traditional iliac bone graft alone

Wound infection · Patients aged 7 to 16 years with unilateral or bilateral cleft lip and palate (alveolar cleft)

Traditional iliac bone graft plus fibrin glue showed no clear difference in postoperative complication: wound infection compared with traditional iliac bone graft alone; GRADE not reported.

1 finding from 1 review

Secondary bone grafting for alveolar cleft in children with cleft lip or cleft lip and palate 2011 · Cochrane All outcomes
At least 3 months
RR 3.23 [0.14, 100]
1 study · 27 participants
GRADE not reported

Traditional iliac bone graft plus fibrin glue vs Traditional iliac bone graft alone

Radiographic assessment: coronal bone density (Hounsfield units) · Patients aged 7 to 16 years with unilateral or bilateral cleft lip and palate (alveolar cleft)

Traditional iliac bone graft plus fibrin glue led to higher radiographic assessment: coronal bone density (Hounsfield units) compared with traditional iliac bone graft alone; GRADE not reported.

1 finding from 1 review

Secondary bone grafting for alveolar cleft in children with cleft lip or cleft lip and palate 2011 · Cochrane All outcomes
At least 3 months
MD 150.89 [3.45, 298.33]
1 study · 27 participants
GRADE not reported

Traditional iliac bone graft plus fibrin glue vs Traditional iliac bone graft alone

Wound dehiscence · Patients aged 7 to 16 years with unilateral or bilateral cleft lip and palate (alveolar cleft)

Traditional iliac bone graft plus fibrin glue showed no clear difference in postoperative complication: wound dehiscence compared with traditional iliac bone graft alone; GRADE not reported.

1 finding from 1 review

Secondary bone grafting for alveolar cleft in children with cleft lip or cleft lip and palate 2011 · Cochrane All outcomes
At least 3 months
RR 0.36 [0.04, 3.03]
1 study · 27 participants
GRADE not reported