Findings

What do systematic reviews say?

7 questions · 7 findings · 1 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 14.3%Moderate 4 · 57.1%High 2 · 28.6%

In‐hospital postoperative mortality · Children having heart surgery with cardiopulmonary bypass

Glucocorticoid showed no clear difference in in‐hospital postoperative mortality compared with placebo (moderate certainty).

1 finding from 1 review

Prophylactic corticosteroids for paediatric heart surgery with cardiopulmonary bypass 2020 · Cochrane Headline outcomes only
RR 0.83 [0.33, 2.07]
5 studies · 313 participants
Moderate

Duration of postoperative mechanical ventilation · Children having heart surgery with cardiopulmonary bypass

1 finding from 1 review

Prophylactic corticosteroids for paediatric heart surgery with cardiopulmonary bypass 2020 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 421 participants
High

Length of postoperative ICU stay · Children having heart surgery with cardiopulmonary bypass

1 finding from 1 review

Prophylactic corticosteroids for paediatric heart surgery with cardiopulmonary bypass 2020 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 421 participants
High

Length of postoperative hospital stay · Children having heart surgery with cardiopulmonary bypass

1 finding from 1 review

Prophylactic corticosteroids for paediatric heart surgery with cardiopulmonary bypass 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 176 participants
Moderate

Mortality within the longest · Children having heart surgery with cardiopulmonary bypass

Glucocorticoid showed no clear difference in all‐cause mortality at longest compared with placebo (moderate certainty).

1 finding from 1 review

Prophylactic corticosteroids for paediatric heart surgery with cardiopulmonary bypass 2020 · Cochrane Headline outcomes only
RR 0.83 [0.33, 2.07]
5 studies · 313 participants
Moderate

Cardiovascular mortality · Children having heart surgery with cardiopulmonary bypass

Glucocorticoid showed no clear difference in cardiovascular mortality at longest compared with placebo (moderate certainty).

1 finding from 1 review

Prophylactic corticosteroids for paediatric heart surgery with cardiopulmonary bypass 2020 · Cochrane Headline outcomes only
RR 0.4 [0.07, 2.46]
3 studies · 109 participants
Moderate

Failure to separate from CPB · Children having heart surgery with cardiopulmonary bypass

Glucocorticoid showed no clear difference in failure to separate from CPB compared with placebo (low certainty).

1 finding from 1 review

Prophylactic corticosteroids for paediatric heart surgery with cardiopulmonary bypass 2020 · Cochrane Headline outcomes only
RR 0.2 [0.01, 3.92]
1 study · 40 participants
Low