Genetically predicted periodontitis vs Without periodontitis (lower genetic liability)
Lacunar stroke · European-ancestry adults
Genetically predicted periodontitis was associated with modestly higher odds of lacunar stroke (OR 1.24); ungraded MR, though the FDR-adjusted P was 0.064 for the primary IVW-FE method (ML-adjusted P 0.037).
1 finding from 1 review
- The contribution of oral infectious diseases in lacunar stroke based on meta-analysis and Mendelian randomization study. 2025 All outcomesGenetic epidemiology (European-ancestry GWAS summary data)OR 1.24 [1.03, 1.49]Studies not reportedGRADE not reported