Genetically predicted DMFS (dental caries) vs Reference (1-SD lower genetically predicted DMFS)
Lumbar spine and pelvis fracture · European-ancestry adults
Genetically predicted dental caries (DMFS) had no significant causal effect on fracture of lumbar spine and pelvis (multivariable MR, OR 0.968).
2 findings from 1 review
- From teeth to bone: dental caries has causal effects on osteoporosis and osteoporotic fracture. 2025 All outcomesLifelong genetic liability · European-ancestry population (two-sample MR: GLIDE exposures; FinnGen osteoporosis/fractures; GeFOS BMD) · MVMR (IVW), adjusted for periodontitisOR 0.968 [0.840, 1.114]490700 participantsGRADE not reported
- From teeth to bone: dental caries has causal effects on osteoporosis and osteoporotic fracture. 2025 All outcomesLifelong genetic liability · European-ancestry population (two-sample MR: GLIDE exposures; FinnGen osteoporosis/fractures; GeFOS BMD) · SVMR (IVW), total causal effectOR 0.950 [0.810, 1.113]490700 participantsGRADE not reported