Genetically predicted DMFS (dental caries) vs Reference (1-SD lower genetically predicted DMFS)
Femur fracture · European-ancestry adults
Genetically predicted dental caries (DMFS) had no significant causal effect on fracture of femur (multivariable MR, OR 1.069).
2 findings from 1 review
- From teeth to bone: dental caries has causal effects on osteoporosis and osteoporotic fracture. 2025 All outcomesLifelong genetic liability · European-ancestry population (two-sample MR: GLIDE exposures; FinnGen osteoporosis/fractures; GeFOS BMD) · MVMR (IVW), adjusted for periodontitisOR 1.069 [0.923, 1.239]489106 participantsGRADE not reported
- From teeth to bone: dental caries has causal effects on osteoporosis and osteoporotic fracture. 2025 All outcomesLifelong genetic liability · European-ancestry population (two-sample MR: GLIDE exposures; FinnGen osteoporosis/fractures; GeFOS BMD) · SVMR (IVW), total causal effectOR 1.126 [0.975, 1.300]489106 participantsGRADE not reported