Findings

What do systematic reviews say?

6 questions · 6 findings · 1 reviews · Heart

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 16.7%Low 2 · 33.3%Moderate 3 · 50%High 0 · 0%

Short‐term mortality (up to 30 days) · Neonates, children and adults undergoing cardiovascular surgery

1 finding from 1 review

Fresh frozen plasma for cardiovascular surgery 2015 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 287 participants
Very low

Blood loss in first 24 hours (neonates and paediatric cases) · Neonates, children and adults undergoing cardiovascular surgery

1 finding from 1 review

Fresh frozen plasma for cardiovascular surgery 2015 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 138 participants
Low

Red cell transfusion requirement in first 24 hours (neonates and paediatric cases) · Neonates, children and adults undergoing cardiovascular surgery

1 finding from 1 review

Fresh frozen plasma for cardiovascular surgery 2015 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 110 participants
Low

Number of participants receiving a red cell transfusion (total) · Neonates, children and adults undergoing cardiovascular surgery

Fresh frozen plasma probably leads to higher number of patients receiving a red cell transfusion compared with no plasma (moderate certainty).

1 finding from 1 review

Fresh frozen plasma for cardiovascular surgery 2015 · Cochrane Headline outcomes only
OR 2.57 [1.3, 5.08]
4 studies · 222 participants
Moderate

Measurement of prothrombin time within 2 hours of infusion · Neonates, children and adults undergoing cardiovascular surgery

1 finding from 1 review

Fresh frozen plasma for cardiovascular surgery 2015 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 210 participants
Moderate

Resource use: need for return to theatre · Neonates, children and adults undergoing cardiovascular surgery

Fresh frozen plasma showed no clear difference in resource use: need for return to theatre compared with no plasma (moderate certainty).

1 finding from 1 review

Fresh frozen plasma for cardiovascular surgery 2015 · Cochrane Headline outcomes only
OR 0.81 [0.26, 2.57]
7 studies · 398 participants
Moderate