Fluorosis (percentage prevalence in permanent teeth) · Children exposed to topical fluoride when under 6 years old; fluorosis assessed in permanent teeth at 6 to 18 years
Used fluoride mouth rinse showed no clear difference in fluorosis (percentage prevalence in permanent teeth) compared with no fluoride mouth rinse; GRADE not reported.
1 finding from 1 review
Caries increment on permanent tooth surfaces (D(M)FS), prevented fraction · Children and adolescents aged 16 years or less
1 finding from 1 review
Caries increment on permanent tooth surfaces (D(M)FS), prevented fraction · Children and adolescents aged 16 years or less
1 finding from 1 review
Unacceptability of treatment (drop-outs / leaving study early) · Children and adolescents aged 16 years or less
Fluoride mouthrinse combined with fluoride toothpaste showed no clear difference in unacceptability of treatment (drop-outs / leaving study early) compared with fluoride mouthrinse alone; GRADE not reported.
1 finding from 1 review
Unacceptability of treatment (drop-outs / leaving study early) · Children and adolescents aged 16 years or less
Fluoride gel combined with fluoride mouthrinse showed no clear difference in unacceptability of treatment (drop-outs / leaving study early) compared with fluoride gel alone; GRADE not reported.
1 finding from 1 review
Caries increment on permanent tooth surfaces (D(M)FS), prevented fraction · Children and adolescents aged 16 years or less
1 finding from 1 review
Caries increment on permanent tooth surfaces (D(M)FS), prevented fraction · Children and adolescents aged 16 years or less
1 finding from 1 review
Unacceptability of treatment (drop-outs / leaving study early) · Children and adolescents aged 16 years or less
Fluoride mouthrinse combined with fluoride toothpaste showed no clear difference in unacceptability of treatment (drop-outs / leaving study early) compared with fluoride toothpaste alone; GRADE not reported.
1 finding from 1 review
Adverse effects (tooth staining and other side effects) · Children and adolescents aged 16 years or less
1 finding from 1 review
Adverse effects: dental fluorosis · Children and adolescents aged 16 years or less
The review found no eligible studies for this question.
1 finding from 1 review
Unacceptability of treatment (drop-outs / leaving study early) · Children and adolescents aged 16 years or less
Fluoride mouthrinse, gel or varnish combined with fluoride… showed no clear difference in unacceptability of treatment (drop-outs / leaving study early) compared with fluoride toothpaste alone; GRADE not reported.
1 finding from 1 review
Caries increment on permanent tooth surfaces (D(M)FS), prevented fraction · Children and adolescents aged 16 years or less
1 finding from 1 review
Dental caries: dmfs increment (primary teeth) · Children and adolescents aged 16 years or less
The review found no eligible studies for this question.
1 finding from 1 review
Proportion developing new caries · Children and adolescents aged 16 years or less
Fluoride mouthrinse (any fluoride agent, concentration, volume,… showed no clear difference in proportion of children developing one or more new caries compared with placebo or no treatment; GRADE not reported.
1 finding from 1 review
Mucosal irritation / oral soft tissue allergic reaction (signs of sensitivity) · Children and adolescents aged 16 years or less
1 finding from 1 review
One trial (Rugg-Gunn 1973) reported incompletely on oral soft tissue irritation/signs of sensitivity (allergic reaction): "no cases of mucosal hypersensitivity after periodical examinations of every subject". 434…
1 study · 434 participants
Very low
Signs of acute toxicity during gel application (nausea, gagging, vomiting) · Children and adolescents aged 16 years or less
The review found no eligible studies for this question.
1 finding from 1 review
Unacceptability of treatment (drop-outs / leaving study early) · Children and adolescents aged 16 years or less
It is very uncertain whether fluoride mouthrinse (any fluoride agent, concentration, volume,… changes unacceptability of treatment as measured by leaving study early… compared with placebo or no treatment (very low certainty).
1 finding from 1 review
Caries increment on permanent whole teeth (D(M)FT), prevented fraction · Children and adolescents aged 16 years or less
1 finding from 1 review
Caries increment on permanent tooth surfaces (D(M)FS), prevented fraction · Children and adolescents aged 16 years or less
1 finding from 1 review
Proportion of children not remaining caries-free · Children and adolescents aged 16 years or less
The review found no eligible studies for this question.
1 finding from 1 review