Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

28 questions · 28 findings · 1 reviews · Headline outcomes only

No studies found 3 · 10.7%GRADE not reported 0 · 0%Very low 0 · 0%Low 8 · 28.6%Moderate 17 · 60.7%High 0 · 0%

First‐line thiazides vs calcium channel blockers

Adverse effects (side effects; treatment withdrawals) · patients with hypertension

First‐line thiazides may leads to lower withdrawals due to adverse effects Duration: 1 to 5 years compared with first‐line calcium channel blockers (low certainty).

1 finding from 1 review