Findings

What do systematic reviews say?

4 questions · 4 findings · 1 reviews · Hypertension

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 4 · 100%Moderate 0 · 0%High 0 · 0%

Total mortality · adults with primary hypertension

First‐line calcium channel blocker showed no clear difference in total mortality compared with placebo (low certainty).

1 finding from 1 review

First‐line drugs for hypertension 2018 · Cochrane Headline outcomes only
RR 0.86 [0.68, 1.09]
1 study · 4695 participants
Low

Stroke · adults with primary hypertension

First‐line calcium channel blocker may leads to lower total stroke compared with placebo (low certainty).

1 finding from 1 review

First‐line drugs for hypertension 2018 · Cochrane Headline outcomes only
RR 0.58 [0.41, 0.84]
1 study · 4695 participants
Low

Total coronary heart disease · adults with primary hypertension

First‐line calcium channel blocker showed no clear difference in total coronary heart disease (CHD) compared with placebo (low certainty).

1 finding from 1 review

First‐line drugs for hypertension 2018 · Cochrane Headline outcomes only
RR 0.77 [0.55, 1.09]
1 study · 4695 participants
Low

Cardiovascular events · adults with primary hypertension

First‐line calcium channel blocker may leads to lower total cardiovascular events compared with placebo (low certainty).

1 finding from 1 review

First‐line drugs for hypertension 2018 · Cochrane Headline outcomes only
RR 0.71 [0.57, 0.87]
1 study · 4695 participants
Low