What do systematic reviews say?

5 questions · 7 findings · 1 reviews · Oral Health

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No studies found 0 · 0%GRADE not reported 7 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Extraction of the permanent first molar vs Not applicable (single-group prevalence)

Spontaneous space closure · Children and adolescents after extraction of a mandibular permanent first molar (before eruption of the second molar)

In the maxilla, spontaneous space closure occurred in about 85% of cases (9 studies; prevalence not GRADE-rated).

3 findings from 1 review

Spontaneous space closure after extraction of permanent first molars in children and adolescents: a systematic review… 2024 All outcomes
Until eruption of the permanent second molar (median follow-up 4.0 years) · University clinics and hospitals in 8 countries (children/adolescents <18 years) · Maxilla
Prevalence 85.3 [73.7, 92.3]
9 studies · 665 participants
GRADE not reported
Spontaneous space closure after extraction of permanent first molars in children and adolescents: a systematic review… 2024 All outcomes
Until eruption of the permanent second molar (median follow-up 4.0 years) · University clinics and hospitals in 8 countries (children/adolescents <18 years) · Mandible
Prevalence 48.1 [34.5, 62.0]
11 studies · 1095 participants
GRADE not reported
Spontaneous space closure after extraction of permanent first molars in children and adolescents: a systematic review… 2024 All outcomes
Until eruption of the permanent second molar (median follow-up 4.0 years) · University clinics and hospitals in 8 countries (children/adolescents <18 years) · Overall (both jaws)
Prevalence 61.6 [50.2, 71.9]
13 studies · 1787 participants
GRADE not reported

Extraction of the mandibular permanent first molar vs Not applicable (single-group prevalence)

Rotation of the mandibular second premolar · Children and adolescents after extraction of a mandibular permanent first molar (before eruption of the second molar)

After mandibular first molar extraction, the second premolar was rotated in about 60% of cases (2 studies; very imprecise; not GRADE-rated).

1 finding from 1 review

Spontaneous space closure after extraction of permanent first molars in children and adolescents: a systematic review… 2024 All outcomes
Until eruption of the permanent second molar (median follow-up 4.0 years) · University clinics and hospitals in 8 countries (children/adolescents <18 years) · Mandible
Prevalence 60.0 [10.7, 95.0]
2 studies · 105 participants
GRADE not reported

Extraction of the mandibular permanent first molar vs Not applicable (single-group prevalence)

Rotation of the mandibular second permanent molar · Children and adolescents after extraction of a mandibular permanent first molar (before eruption of the second molar)

After mandibular first molar extraction, the second molar was rotated in about 77% of cases (2 studies; very imprecise; not GRADE-rated).

1 finding from 1 review

Spontaneous space closure after extraction of permanent first molars in children and adolescents: a systematic review… 2024 All outcomes
Until eruption of the permanent second molar (median follow-up 4.0 years) · University clinics and hospitals in 8 countries (children/adolescents <18 years) · Mandible
Prevalence 76.9 [15.5, 98.4]
2 studies · 108 participants
GRADE not reported

Extraction of the mandibular permanent first molar vs Not applicable (single-group prevalence)

Rotation of the mandibular first premolar · Children and adolescents after extraction of a mandibular permanent first molar (before eruption of the second molar)

After mandibular first molar extraction, the first premolar was rotated in about 38% of cases (2 studies; very imprecise; not GRADE-rated).

1 finding from 1 review

Spontaneous space closure after extraction of permanent first molars in children and adolescents: a systematic review… 2024 All outcomes
Until eruption of the permanent second molar (median follow-up 4.0 years) · University clinics and hospitals in 8 countries (children/adolescents <18 years) · Mandible
Prevalence 37.8 [0.7, 98.2]
2 studies · 109 participants
GRADE not reported

Unilateral extraction of the mandibular first permanent molar vs Bilateral extraction of the mandibular first permanent molars

Midline deviation of the mandibular arch · Children and adolescents after extraction of a mandibular permanent first molar (before eruption of the second molar)

One study found midline deviation more likely after unilateral than bilateral extraction (OR 11.6; single study; not GRADE-rated).

1 finding from 1 review

Spontaneous space closure after extraction of permanent first molars in children and adolescents: a systematic review… 2024 All outcomes
Until eruption of the permanent second molar (median follow-up 4.0 years) · University clinics and hospitals in 8 countries (children/adolescents <18 years) · Mandible
OR 11.6 [1.9, 70.3]
1 study
GRADE not reported