Findings

What do systematic reviews say?

3 questions · 3 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 3 · 100%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Etretinate vs placebo or no treatment

Proportion of participants with adverse effects ‐ measured over 8 weeks · chronic palmoplantar pustulosis

It is very uncertain whether etretinate changes proportion of participants with adverse effects ‐ measured over 12… compared with placebo or no treatment (very low certainty).

1 finding from 1 review

Interventions for chronic palmoplantar pustulosis 2020 · Cochrane Headline outcomes only
RR 3.5 [0.95, 12.9]
1 study · 20 participants
Very low

Etretinate vs PUVA

Proportion of participants with adverse effects ‐ measured over 8 weeks · chronic palmoplantar pustulosis

It is very uncertain whether etretinate changes proportion of participants with adverse effects ‐ measured over 12… compared with PUVA therapy (very low certainty).

1 finding from 1 review

Interventions for chronic palmoplantar pustulosis 2020 · Cochrane Headline outcomes only
RR 11.54 [5.17, 25.74]
1 study · 84 participants
Very low

Etretinate with PUVA therapy as co‐intervention vs placebo with PUVA therapy

Proportion of participants with adverse effects ‐ measured over 8 weeks · chronic palmoplantar pustulosis

It is very uncertain whether etretinate with PUVA therapy as co‐intervention changes proportion of participants with adverse effects ‐ measured over 20… compared with placebo with PUVA therapy (very low certainty).

1 finding from 1 review

Interventions for chronic palmoplantar pustulosis 2020 · Cochrane Headline outcomes only
RR 17 [1.11, 259.87]
1 study · 20 participants
Very low