Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

44 questions · 44 findings · 3 reviews · Headline outcomes only

No studies found 14 · 31.8%GRADE not reported 0 · 0%Very low 13 · 29.5%Low 11 · 25%Moderate 6 · 13.6%High 0 · 0%

Epidural analgesia vs peripheral nerve blocks

Pain at rest at 6 to 8 hours (score from 0 to 10) · adults undergoing cardiac surgery without cardiopulmonary bypass

It is very uncertain whether epidural analgesia changes pain at rest at 6 to 8hours after surgery (score from 0 to 10) compared with peripheral nerve blocks (very low certainty).

1 finding from 1 review

Epidural analgesia vs systemic analgesia

Vomiting · children having undergone thoraco‐lumbar spine surgery. 3 trials included in the analysis contained participants older than 18 years:…

Epidural analgesia showed no clear difference in vomiting up to 48 hours after surgery compared with systemic analgesia (low certainty).

1 finding from 1 review

Epidural analgesia vs peripheral nerve blocks

Duration of tracheal intubation · adults undergoing cardiac surgery without cardiopulmonary bypass

It is very uncertain whether epidural analgesia changes duration of tracheal intubation compared with peripheral nerve blocks (very low certainty).

1 finding from 1 review

Epidural analgesia vs intrapleural analgesia

Duration of tracheal intubation · adults undergoing cardiac surgery without cardiopulmonary bypass

It is very uncertain whether epidural analgesia changes duration of tracheal intubation compared with intrapleural analgesia (very low certainty).

1 finding from 1 review

Epidural analgesia vs intrapleural analgesia

Pain at rest at 6 to 8 hours (score from 0 to 10) · adults undergoing cardiac surgery without cardiopulmonary bypass

Epidural analgesia may leads to higher pain at rest at 6 to 8 hours (score from 0 to 10) compared with intrapleural analgesia (low certainty).

1 finding from 1 review