What do systematic reviews say?

Enteral zinc supplementation vs no zinc supplementation

Enteral zinc supplementation may leads to lower all‐cause mortality (between start of intervention and end of compared with no zinc supplementation (low certainty).

• Enteral zinc supplementation for prevention of morbidity and mortality in preterm neonates 2021 · Cochrane Headline outcomes only
  RR 0.55 [0.31, 0.97]
  3 studies · 345 participants
  Low

Enteral zinc supplementation vs no zinc supplementation

• Enteral zinc supplementation for prevention of morbidity and mortality in preterm neonates 2021 · Cochrane Headline outcomes only
  no estimate extracted
  0 participants
  GRADE not reported

Enteral zinc supplementation vs no zinc supplementation

Enteral zinc supplementation showed no clear difference in bronchopulmonary dysplasia compared with no zinc supplementation (low certainty).

• Enteral zinc supplementation for prevention of morbidity and mortality in preterm neonates 2021 · Cochrane Headline outcomes only
  RR 0.66 [0.31, 1.4]
  1 study · 193 participants
  Low

Enteral zinc supplementation vs no zinc supplementation

Enteral zinc supplementation showed no clear difference in retinopathy of prematurity compared with no zinc supplementation (low certainty).

• Enteral zinc supplementation for prevention of morbidity and mortality in preterm neonates 2021 · Cochrane Headline outcomes only
  RR 0.14 [0.01, 2.7]
  1 study · 193 participants
  Low

Enteral zinc supplementation vs no zinc supplementation

Enteral zinc supplementation showed no clear difference in bacterial sepsis compared with no zinc supplementation (moderate certainty).

• Enteral zinc supplementation for prevention of morbidity and mortality in preterm neonates 2021 · Cochrane Headline outcomes only
  RR 1.11 [0.6, 2.04]
  2 studies · 293 participants
  Moderate

Enteral zinc supplementation vs no zinc supplementation

Enteral zinc supplementation showed no clear difference in necrotising enterocolitis compared with no zinc supplementation (low certainty).

• Enteral zinc supplementation for prevention of morbidity and mortality in preterm neonates 2021 · Cochrane Headline outcomes only
  RR 0.08 [0, 1.33]
  1 study · 193 participants
  Low

Enteral zinc supplementation vs no zinc supplementation

The review found no eligible studies for this question.

• Enteral zinc supplementation for prevention of morbidity and mortality in preterm neonates 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found