What do systematic reviews say?

Endovenous laser ablation (EVLA) vs radiofrequency ablation

Endovenous laser ablation (EVLA) showed no clear difference in technical success (< 5 years) compared with radiofrequency ablation (RFA) (moderate certainty).

• Interventions for great saphenous vein incompetence 2021 · Cochrane Headline outcomes only
  OR 0.98 [0.41, 2.38]
  5 studies · 780 participants
  Moderate
• Interventions for great saphenous vein incompetence 2021 · Cochrane Headline outcomes only
  OR 0.85 [0.3, 2.41]
  1 study · 291 participants
  Low

Endovenous laser ablation (EVLA) vs radiofrequency ablation

Endovenous laser ablation (EVLA) showed no clear difference in recurrence (< 5 years) compared with radiofrequency ablation (RFA) (low certainty).

• Interventions for great saphenous vein incompetence 2021 · Cochrane Headline outcomes only
  OR 1.53 [0.78, 2.99]
  1 study · 291 participants
  Low

Endovenous laser ablation (EVLA) vs radiofrequency ablation

Endovenous laser ablation (EVLA) may leads to higher long‐term recurrence (> 5 years) compared with radiofrequency ablation (RFA) (low certainty).

• Interventions for great saphenous vein incompetence 2021 · Cochrane Headline outcomes only
  OR 2.77 [1.52, 5.06]
  1 study · 291 participants
  Low

Endovenous laser ablation (EVLA) vs radiofrequency ablation

• Interventions for great saphenous vein incompetence 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  Very low

Endovenous laser ablation (EVLA) vs radiofrequency ablation

• Interventions for great saphenous vein incompetence 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  Moderate

Endovenous laser ablation (EVLA) vs conventional surgery

Endovenous laser ablation probably leads to lower recanalisation or persistence of reflux at 6 weeks compared with conventional surgery (moderate certainty).

• Endovenous ablation therapy (laser or radiofrequency) or foam sclerotherapy versus conventional surgical repair for… 2016 · Cochrane Headline outcomes only
  OR 0.07 [0.02, 0.22]
  3 studies · 289 participants
  Moderate

Endovenous laser ablation (EVLA) vs conventional surgery

Endovenous laser ablation may leads to lower recurrence of reflux at 1 year compared with conventional surgery (low certainty).

• Endovenous ablation therapy (laser or radiofrequency) or foam sclerotherapy versus conventional surgical repair for… 2016 · Cochrane Headline outcomes only
  OR 0.24 [0.07, 0.77]
  2 studies · 119 participants
  Low

Endovenous laser ablation (EVLA) vs conventional surgery

Endovenous laser ablation showed no clear difference in clinical evidence of recurrence after 1 year compared with conventional surgery (low certainty).

• Endovenous ablation therapy (laser or radiofrequency) or foam sclerotherapy versus conventional surgical repair for… 2016 · Cochrane Headline outcomes only
  OR 0.54 [0.17, 1.75]
  1 study · 99 participants
  Low

Endovenous laser ablation (EVLA) vs conventional surgery

• Endovenous ablation therapy (laser or radiofrequency) or foam sclerotherapy versus conventional surgical repair for… 2016 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 99 participants
  Moderate

Endovenous laser ablation (EVLA) vs conventional surgery

• Endovenous ablation therapy (laser or radiofrequency) or foam sclerotherapy versus conventional surgical repair for… 2016 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 265 participants
  Moderate
• Endovenous ablation therapy (laser or radiofrequency) or foam sclerotherapy versus conventional surgical repair for… 2016 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 99 participants
  Low

Endovenous laser ablation (EVLA) vs conventional surgery

• Endovenous ablation therapy (laser or radiofrequency) or foam sclerotherapy versus conventional surgical repair for… 2016 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 265 participants
  Moderate