Findings

What do systematic reviews say?

5 questions · 5 findings · 1 reviews · Oral medicine and oral cancer

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No studies found 1 · 20%GRADE not reported 0 · 0%Very low 3 · 60%Low 1 · 20%Moderate 0 · 0%High 0 · 0%

Elective radical (comprehensive) neck dissection vs Elective selective neck dissection

Total mortality · Adults with oral cavity cancer

1 finding from 1 review

Interventions for the treatment of oral cavity and oropharyngeal cancers: surgical treatment 2023 · Cochrane All outcomes
Total mortality: 2 trials reported HR but could not be pooled (different surgical procedures); neither indicated a difference (BHNCSG 1998 HR 1.14, 0.70 to 1.86; Bier 1994 HR 0.87, 0.41 to 1.83); 252 participants (2…
2 studies · 252 participants
Very low

Elective radical (comprehensive) neck dissection vs Elective selective neck dissection

Locoregional recurrence · Adults with oral cavity cancer

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for the treatment of oral cavity and oropharyngeal cancers: surgical treatment 2023 · Cochrane All outcomes
Locoregional recurrence: not reported.
0 studies
No studies found

Elective radical (comprehensive) neck dissection vs Elective selective neck dissection

Adverse events associated with treatment · Adults with oral cavity cancer

1 finding from 1 review

Interventions for the treatment of oral cavity and oropharyngeal cancers: surgical treatment 2023 · Cochrane All outcomes
Adverse events (BHNCSG 1998): flap necrosis, wound infection, fistula, vascular rupture, haematoma, seroma, chyle fistula; no complications in 45/76 modified radical ND and 54/72 supraomohyoid ND; 2 vs 1 postoperative…
1 study · 148 participants
Low

Elective radical (comprehensive) neck dissection vs Elective selective neck dissection

Recurrence · Adults with oral cavity cancer

It is very uncertain whether elective radical (comprehensive) neck dissection changes recurrence compared with elective selective neck dissection (very low certainty).

1 finding from 1 review

Interventions for the treatment of oral cavity and oropharyngeal cancers: surgical treatment 2023 · Cochrane All outcomes
5 years
RR 1.21 [0.63, 2.33]
1 study · 143 participants
Very low

Elective radical (comprehensive) neck dissection vs Elective selective neck dissection

Disease-free survival · Adults with oral cavity cancer

It is very uncertain whether elective radical (comprehensive) neck dissection changes disease-free survival (new disease, progression, and mortality) compared with elective selective neck dissection (very low certainty).

1 finding from 1 review

Interventions for the treatment of oral cavity and oropharyngeal cancers: surgical treatment 2023 · Cochrane All outcomes
5 years
HR 0.57 [0.29, 1.11]
1 study · 104 participants
Very low