The review found no eligible studies for this question.
Early physical therapy showed no clear difference in occurrence of CIP/CIM ‐ in the total population randomised compared with control (low certainty).
Early physical therapy probably leads to lower occurrence of CIP/CIM ‐ in screened population compared with control (moderate certainty).
Early physical therapy showed no clear difference in serious adverse events ‐ in total population randomised compared with control (moderate certainty).
Early taxane‐based chemotherapy and androgen deprivation therapy (ADT) probably leads to lower time to death due to any cause (absolute effect size estimates based… compared with ADT only (moderate certainty).
Early taxane‐based chemotherapy and androgen deprivation therapy (ADT) may leads to higher grade III to V adverse events compared with ADT only (low certainty).
Early taxane‐based chemotherapy and androgen deprivation therapy (ADT) probably leads to lower prostate cancer‐specific death5 compared with ADT only (moderate certainty).
Early taxane‐based chemotherapy and androgen deprivation therapy (ADT) probably leads to lower time to progression (absolute effect size estimates based on… compared with ADT only (moderate certainty).
Early taxane‐based chemotherapy and androgen deprivation therapy (ADT) may leads to higher discontinuation due to adverse events compared with ADT only (low certainty).
Early taxane‐based chemotherapy and androgen deprivation therapy (ADT) may leads to higher all adverse events compared with ADT only (low certainty).
Early showed no clear difference in death at day 30Â compared with standard initiation of kidney replacement therapy (KRT) (low certainty).
Early showed no clear difference in death after 30 days compared with standard initiation of kidney replacement therapy (KRT) (moderate certainty).
Early showed no clear difference in death or non‐recovery of kidney function Time frame: day 90 compared with standard initiation of kidney replacement therapy (KRT) (low certainty).
Early showed no clear difference in recovery of kidney function Patients free from KRT according to ITT… compared with standard initiation of kidney replacement therapy (KRT) (low certainty).
Early leads to higher adverse events: hypophosphataemia compared with standard initiation of kidney replacement therapy (KRT) (high certainty).
Early leads to higher adverse events: hypotension compared with standard initiation of kidney replacement therapy (KRT) (high certainty).
Early leads to higher adverse events: cardiac‐rhythm disorder compared with standard initiation of kidney replacement therapy (KRT) (high certainty).
Early showed no clear difference in adverse events: infection compared with standard initiation of kidney replacement therapy (KRT) (high certainty).