Findings

What do systematic reviews say?

2 questions · 2 findings · 1 reviews · Epilepsy

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 2 · 100%Moderate 0 · 0%High 0 · 0%

Early vs late AED withdrawal

Seizure relapse rate by time of withdrawal · individuals with epilepsy in remission

Early may leads to higher seizure relapse rate by time of withdrawal compared with late AED withdrawal (low certainty).

1 finding from 1 review

Early versus late antiepileptic drug withdrawal for people with epilepsy in remission 2015 · Cochrane Headline outcomes only
RR 1.34 [1.13, 1.59]
5 studies · 924 participants
Low

Early vs late AED withdrawal

Seizure relapse rate in people with partial epilepsy by time of withdrawal · individuals with epilepsy in remission

Early showed no clear difference in seizure relapse rate in people with partial epilepsy by time of… compared with late AED withdrawal (low certainty).

1 finding from 1 review

Early versus late antiepileptic drug withdrawal for people with epilepsy in remission 2015 · Cochrane Headline outcomes only
RR 1.51 [0.97, 2.35]
2 studies · 180 participants
Low