All adverse events
Early taxane‐based chemotherapy and androgen deprivation therapy (ADT) may leads to higher all adverse events compared with ADT only (low certainty).
1 finding from 1 review
Quality of life at 12 months (
1 finding from 1 review
Secondary alveolar bone grafting performed at one timing (e.g. early secondary grafting) vs Secondary alveolar bone grafting performed at a different / optimal timing (e.g. late secondary grafting)
Outcome not reported · Patients greater than 5 years of age with unilateral or bilateral cleft lip and/or palate involving the alveolar process (complete or…
The review found no eligible studies for this question.
1 finding from 1 review
Self concept · Children (7 to 11 years) and adolescents (12 to 16 years) with prominent upper front teeth (Class II malocclusion)
Early treatment (two-phase: phase 1 in childhood, phase 2 in… showed no clear difference in self concept compared with late treatment (one-phase in adolescence) with functional appliance; GRADE not reported.
2 findings from 1 review
Incidence of new incisal trauma · Children (7 to 11 years) and adolescents (12 to 16 years) with prominent upper front teeth (Class II malocclusion)
Early treatment (two-phase: phase 1 in childhood, phase 2 in… probably leads to lower incidence of new incisal trauma compared with late treatment (one-phase in adolescence) with functional appliance (moderate certainty).
1 finding from 1 review
Final overjet · Children (7 to 11 years) and adolescents (12 to 16 years) with prominent upper front teeth (Class II malocclusion)
Early treatment (two-phase: phase 1 in childhood, phase 2 in… led to lower final overjet compared with late treatment (one-phase in adolescence) with functional appliance; GRADE not reported.
2 findings from 1 review
Final ANB · Children (7 to 11 years) and adolescents (12 to 16 years) with prominent upper front teeth (Class II malocclusion)
Early treatment (two-phase: phase 1 in childhood, phase 2 in… led to lower final ANB compared with late treatment (one-phase in adolescence) with functional appliance; GRADE not reported.
2 findings from 1 review
Incidence of incisal trauma · Children (7 to 11 years) and adolescents (12 to 16 years) with prominent upper front teeth (Class II malocclusion)
Early treatment (two-phase: phase 1 in childhood, phase 2 in… showed no clear difference in incidence of incisal trauma compared with late treatment (one-phase in adolescence) with functional appliance; GRADE not reported.
1 finding from 1 review
PAR score · Children (7 to 11 years) and adolescents (12 to 16 years) with prominent upper front teeth (Class II malocclusion)
Early treatment (two-phase: phase 1 in childhood, phase 2 in… led to lower PAR score compared with late treatment (one-phase in adolescence) with functional appliance; GRADE not reported.
2 findings from 1 review
MD -10.52 [-12.32, -8.71]
2 studies · 349 participants
GRADE not reported
MD 0.62 [-0.66, 1.91]
3 studies · 360 participants
GRADE not reported