Findings

What do systematic reviews say?

4 questions · 4 findings · 1 reviews · Headline outcomes only

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 2 · 50%Moderate 2 · 50%High 0 · 0%

total treatment failure · patients with human Brucellosis

Doxycycline+Rifampicin probably leads to higher total treatment failure compared with doxycycline+Streptomycin (moderate certainty).

1 finding from 1 review

Antibiotics for treating human brucellosis 2012 · Cochrane Headline outcomes only
RR 1.91 [1.07, 3.42]
7 studies · 567 participants
Moderate

Minor adverse drug reactions · patients with human Brucellosis

Doxycycline+Rifampicin showed no clear difference in minor adverse drug reactions compared with doxycycline+Streptomycin (low certainty).

1 finding from 1 review

Antibiotics for treating human brucellosis 2012 · Cochrane Headline outcomes only
RR 1.38 [0.99, 1.92]
5 studies · 473 participants
Low

total treatment failure · patients with human Brucellosis

Doxycycline+Rifampicin showed no clear difference in total treatment failure compared with quinolones+Rifampicin (moderate certainty).

1 finding from 1 review

Antibiotics for treating human brucellosis 2012 · Cochrane Headline outcomes only
OR 0.94 [0.45, 1.98]
3 studies · 181 participants
Moderate

Minor adverse drug reactions · patients with human Brucellosis

Doxycycline+Rifampicin showed no clear difference in minor adverse drug reactions compared with quinolones+Rifampicin (low certainty).

1 finding from 1 review

Antibiotics for treating human brucellosis 2012 · Cochrane Headline outcomes only
RR 1.8 [0.78, 4.18]
4 studies · 296 participants
Low