Findings

What do systematic reviews say?

7 questions · 8 findings · 1 reviews · Pain, Palliative and Supportive Care

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No studies found 1 · 12.5%GRADE not reported 2 · 25%Very low 5 · 62.5%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Diclofenac vs paracetamol

Outcome№ of participants(studies) · children with acute postoperative pain

The review found no eligible studies for this question.

1 finding from 1 review

Diclofenac for acute postoperative pain in children 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Diclofenac vs paracetamol

Relief of pain · children with acute postoperative pain

2 findings from 1 review

Diclofenac for acute postoperative pain in children 2023 · Cochrane Headline outcomes only
no estimate extracted
50 participants
GRADE not reported
Diclofenac for acute postoperative pain in children 2023 · Cochrane Headline outcomes only
no estimate extracted
50 participants
GRADE not reported

Diclofenac vs paracetamol

Pain intensity ‐ as reported by child, at 0 to 2 hours № of participants: 180 (2 RCTs) · children with acute postoperative pain

1 finding from 1 review

Diclofenac for acute postoperative pain in children 2023 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 2 participants
Very low

Diclofenac vs paracetamol

Pain intensity ‐ as reported by child, at 2 to 24 hours № of participants: 300 (3 RCTs) · children with acute postoperative pain

1 finding from 1 review

Diclofenac for acute postoperative pain in children 2023 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 3 participants
Very low

Diclofenac vs paracetamol

Nausea and vomiting · children with acute postoperative pain

It is very uncertain whether diclofenac changes nausea, vomiting, or both during study period № of participants: 348… compared with paracetamol (very low certainty).

1 finding from 1 review

Diclofenac for acute postoperative pain in children 2023 · Cochrane Headline outcomes only
RR 0.47 [0.25, 0.87]
5 studies · 348 participants
Very low

Diclofenac vs paracetamol

Any bleeding during study period № of participants: 100(2 RCTs)d · children with acute postoperative pain

It is very uncertain whether diclofenac changes any bleeding during study period № of participants: 332 (5 RCTs) compared with paracetamol (very low certainty).

1 finding from 1 review

Diclofenac for acute postoperative pain in children 2023 · Cochrane Headline outcomes only
RR 0.57 [0.12, 2.62]
5 studies · 332 participants
Very low

Diclofenac vs paracetamol

Serious adverse events during the study period · children with acute postoperative pain

It is very uncertain whether diclofenac changes serious adverse events during study period № of participants: 60 (1… compared with paracetamol (very low certainty).

1 finding from 1 review

Diclofenac for acute postoperative pain in children 2023 · Cochrane Headline outcomes only
RR 0.5 [0.05, 5.22]
1 study · 60 participants
Very low