Findings

What do systematic reviews say?

7 questions · 8 findings · 1 reviews

No studies found 2 · 25%GRADE not reported 3 · 37.5%Very low 1 · 12.5%Low 0 · 0%Moderate 2 · 25%High 0 · 0%

Relief of pain · children with acute postoperative pain

2 findings from 1 review

Diclofenac for acute postoperative pain in children 2023 · Cochrane Headline outcomes only
no estimate extracted
50 participants
GRADE not reported
Diclofenac for acute postoperative pain in children 2023 · Cochrane Headline outcomes only
no estimate extracted
50 participants
GRADE not reported

Reduction in pain intensity · children with acute postoperative pain

1 finding from 1 review

Diclofenac for acute postoperative pain in children 2023 · Cochrane Headline outcomes only
no estimate extracted
0 participants
GRADE not reported

Pain intensity ‐ as reported by child, at 2 to 24 hours № of participants: 300 (3 RCTs) · children with acute postoperative pain

1 finding from 1 review

Diclofenac for acute postoperative pain in children 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 2 participants
Very low

Nausea and vomiting · children with acute postoperative pain

Diclofenac probably leads to lower nausea, vomiting, or both during study period № of participants: 463… compared with opioids (moderate certainty).

1 finding from 1 review

Diclofenac for acute postoperative pain in children 2023 · Cochrane Headline outcomes only
RR 0.75 [0.58, 0.96]
7 studies · 463 participants
Moderate

Any bleeding during study period № of participants: 100(2 RCTs)d · children with acute postoperative pain

Diclofenac probably leads to higher any bleeding during study period № of participants: 222 (2 RCTs) compared with opioids (moderate certainty).

1 finding from 1 review

Diclofenac for acute postoperative pain in children 2023 · Cochrane Headline outcomes only
RR 3.06 [1.31, 7.13]
2 studies · 222 participants
Moderate

Serious adverse events during the study period · children with acute postoperative pain

The review found no eligible studies for this question.

1 finding from 1 review

Diclofenac for acute postoperative pain in children 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Outcome№ of participants(studies) · children with acute postoperative pain

The review found no eligible studies for this question.

1 finding from 1 review

Diclofenac for acute postoperative pain in children 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found