Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

52 questions · 52 findings · 6 reviews

No studies found 9 · 17.3%GRADE not reported 2 · 3.8%Very low 10 · 19.2%Low 14 · 26.9%Moderate 13 · 25%High 4 · 7.7%

Corticosteroids (dexamethasone) vs placebo

Number of participants with normal physical joint function ‐ normal function at 12 months of · septic arthritis in children taking antibiotics

Corticosteroids (dexamethasone) may leads to higher number of participants with normal physical joint function ‐ normal… compared with placebo (low certainty).

1 finding from 1 review

Corticosteroids (dexamethasone) vs placebo

Number of days of antibiotic treatment ‐ number of days of intravenous antibiotic treatment · septic arthritis in children taking antibiotics

Corticosteroids (dexamethasone) showed no clear difference in number of days of antibiotic treatment ‐ number of days of… compared with placebo (low certainty).

1 finding from 1 review

Dexamethasone vs betamethasone – child outcomes

Developmental delay –motor (mild, moderate or severe) · women at risk of preterm birth

Dexamethasone showed no clear difference in developmental delay –motor (mild, moderate or severe) compared with betamethasone – child outcomes (moderate certainty).

1 finding from 1 review

Dexamethasone vs betamethasone – child outcomes

Intellectual impairment: developmental delay – cognitive or language (mild, moderate or severe) · women at risk of preterm birth

Dexamethasone showed no clear difference in intellectual impairment: developmental delay – cognitive or language… compared with betamethasone – child outcomes (moderate certainty).

1 finding from 1 review

Dexamethasone vs betamethasone – maternal outcomes

Maternal adverse effects of therapy · women at risk of preterm birth

Dexamethasone showed no clear difference in maternal adverse effects of therapy compared with betamethasone – maternal outcomes (moderate certainty).

1 finding from 1 review

Dexamethasone vs betamethasone – child outcomes

Any known death after randomisation (fetal, neonatal, child, child as adult) · women at risk of preterm birth

Dexamethasone showed no clear difference in any known death after randomisation (fetal, neonatal, child, child… compared with betamethasone – fetal/neonatal outcomes (moderate certainty).

1 finding from 1 review