Findings

What do systematic reviews say?

35 questions · 42 findings · 1 reviews · Urology

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No studies found 16 · 38.1%GRADE not reported 0 · 0%Very low 4 · 9.5%Low 16 · 38.1%Moderate 6 · 14.3%High 0 · 0%

Desmopressin vs placebo

Number of nocturnal voids

2 findings from 1 review

Desmopressin for treating nocturia in men 2017 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 1982 participants
Low
Desmopressin for treating nocturia in men 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 115 participants
Low

Desmopressin vs placebo

Major adverse events

Desmopressin showed no clear difference in major adverse events compared with placebo (low certainty).

2 findings from 1 review

Desmopressin for treating nocturia in men 2017 · Cochrane Headline outcomes only
RR 3.05 [0.13, 73.39]
1 study · 115 participants
Low
Desmopressin for treating nocturia in men 2017 · Cochrane Headline outcomes only
RR 0.97 [0.1, 9.03]
2 studies · 536 participants
Very low

Desmopressin vs placebo

Duration of first sleep episode

2 findings from 1 review

Desmopressin for treating nocturia in men 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 115 participants
Moderate
Desmopressin for treating nocturia in men 2017 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 652 participants
Very low

Desmopressin vs placebo

Time to first void ‐ not reported

The review found no eligible studies for this question.

2 findings from 1 review

Desmopressin for treating nocturia in men 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found
Desmopressin for treating nocturia in men 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 383 participants
Low

Desmopressin vs placebo

Minor adverse events

Desmopressin showed no clear difference in minor adverse events compared with placebo (low certainty).

2 findings from 1 review

Desmopressin for treating nocturia in men 2017 · Cochrane Headline outcomes only
RR 0.86 [0.49, 1.49]
1 study · 115 participants
Low
Desmopressin for treating nocturia in men 2017 · Cochrane Headline outcomes only
RR 0.87 [0.67, 1.13]
3 studies · 594 participants
Low

Desmopressin vs placebo

Withdrawals due to adverse events

Desmopressin showed no clear difference in treatment withdrawal due to adverse event compared with placebo (low certainty).

2 findings from 1 review

Desmopressin for treating nocturia in men 2017 · Cochrane Headline outcomes only
RR 3.05 [0.13, 73.39]
1 study · 115 participants
Low
Desmopressin for treating nocturia in men 2017 · Cochrane Headline outcomes only
RR 1.1 [0.56, 2.15]
4 studies · 614 participants
Low

Desmopressin vs behaviour modifications

Number of nocturnal voids ‐ not reported

The review found no eligible studies for this question.

1 finding from 1 review

Desmopressin for treating nocturia in men 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Desmopressin vs behaviour modifications

Quality of life ‐ not reported

The review found no eligible studies for this question.

1 finding from 1 review

Desmopressin for treating nocturia in men 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Desmopressin vs behaviour modifications

Major adverse events

The review found no eligible studies for this question.

1 finding from 1 review

Desmopressin for treating nocturia in men 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Desmopressin vs behaviour modifications

Duration of first sleep episode

1 finding from 1 review

Desmopressin for treating nocturia in men 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 60 participants
Low

Desmopressin vs behaviour modifications

Time to first void ‐ not reported

The review found no eligible studies for this question.

1 finding from 1 review

Desmopressin for treating nocturia in men 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Desmopressin vs placebo

Quality of life ‐ not reported

The review found no eligible studies for this question.

2 findings from 1 review

Desmopressin for treating nocturia in men 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found
Desmopressin for treating nocturia in men 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Desmopressin vs behaviour modifications

Minor adverse events ‐ not reported

The review found no eligible studies for this question.

1 finding from 1 review

Desmopressin for treating nocturia in men 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Desmopressin vs behaviour modifications

Withdrawals due to adverse outcomes

The review found no eligible studies for this question.

1 finding from 1 review

Desmopressin for treating nocturia in men 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Desmopressin vs alpha‐blocker

Number of nocturnal voids

1 finding from 1 review

Desmopressin for treating nocturia in men 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 31 participants
Moderate

Desmopressin vs alpha‐blocker

Quality of life

1 finding from 1 review

Desmopressin for treating nocturia in men 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 31 participants
Moderate

Desmopressin vs alpha‐blocker

Major adverse events

1 finding from 1 review

Desmopressin for treating nocturia in men 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 31 participants
Low

Desmopressin vs alpha‐blocker

Duration of first sleep episode ‐ not reported

The review found no eligible studies for this question.

1 finding from 1 review

Desmopressin for treating nocturia in men 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Desmopressin vs alpha‐blocker

Time to first void ‐ not reported

The review found no eligible studies for this question.

1 finding from 1 review

Desmopressin for treating nocturia in men 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Desmopressin vs alpha‐blocker

Minor adverse events

It is very uncertain whether desmopressin changes minor adverse events compared with alpha‐blocker (very low certainty).

1 finding from 1 review

Desmopressin for treating nocturia in men 2017 · Cochrane Headline outcomes only
RR 1.07 [0.07, 15.57]
1 study · 31 participants
Very low