Desmopressin vs alpha‐blocker
Withdrawals due to adverse events
1 finding from 1 review
- no estimate extracted1 study · 31 participantsLow
Findings
What do systematic reviews say?
35 questions · 42 findings · 1 reviews
No studies found 16 · 38.1%GRADE not reported 0 · 0%Very low 4 · 9.5%Low 16 · 38.1%Moderate 6 · 14.3%High 0 · 0%
Desmopressin plus alpha‐blocker vs alpha‐blocker
Number of nocturnal voids
1 finding from 1 review
- no estimate extracted3 studies · 341 participantsModerate
Desmopressin plus alpha‐blocker vs alpha‐blocker
Quality of life
1 finding from 1 review
- no estimate extracted3 studies · 341 participantsModerate
Desmopressin plus alpha‐blocker vs alpha‐blocker
Major adverse events
Desmopressin plus alpha‐blocker showed no clear difference in major adverse events compared with alpha‐blocker (low certainty).
1 finding from 1 review
- RR 0.3 [0.01, 7.32]3 studies · 402 participantsLow
Desmopressin plus alpha‐blocker vs alpha‐blocker
Duration of first sleep episode ‐ not reported
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Desmopressin plus alpha‐blocker vs alpha‐blocker
Time to first void ‐ not reported
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Desmopressin plus alpha‐blocker vs alpha‐blocker
Minor adverse events
It is very uncertain whether desmopressin plus alpha‐blocker changes minor adverse events compared with alpha‐blocker (very low certainty).
1 finding from 1 review
- RR 1.6 [0.15, 16.82]3 studies · 402 participantsVery low
Desmopressin plus alpha‐blocker vs alpha‐blocker
Withdrawals due to adverse events
Desmopressin plus alpha‐blocker showed no clear difference in treatment withdrawal due to adverse event compared with alpha‐blocker (low certainty).
1 finding from 1 review
- RR 2.84 [0.46, 17.66]3 studies · 402 participantsLow
Desmopressin plus alpha‐blocker vs alpha‐blocker plus anticholinergic
Number of nocturnal voids
1 finding from 1 review
- no estimate extracted1 study · 405 participantsModerate
Desmopressin plus alpha‐blocker vs alpha‐blocker plus anticholinergic
Quality of life ‐ not reported
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Desmopressin plus alpha‐blocker vs alpha‐blocker plus anticholinergic
Major adverse events
1 finding from 1 review
- no estimate extracted1 study · 427 participantsLow
Desmopressin plus alpha‐blocker vs alpha‐blocker plus anticholinergic
Duration of first sleep episode ‐ not reported
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Desmopressin plus alpha‐blocker vs alpha‐blocker plus anticholinergic
Time to first void ‐ not reported
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Desmopressin plus alpha‐blocker vs alpha‐blocker plus anticholinergic
Minor adverse events
Desmopressin plus alpha‐blocker may leads to lower minor adverse events compared with alpha‐blocker plus anticholinergic (low certainty).
1 finding from 1 review
- RR 0.22 [0.05, 0.98]1 study · 427 participantsLow
Desmopressin plus alpha‐blocker vs alpha‐blocker plus anticholinergic
Withdrawals due to adverse events
Desmopressin plus alpha‐blocker may leads to lower treatment withdrawal due to adverse event compared with alpha‐blocker plus anticholinergic (low certainty).
1 finding from 1 review
- RR 0.22 [0.05, 0.98]1 study · 427 participantsLow