What do systematic reviews say?

Desmopressin vs placebo

Desmopressin showed no clear difference in treatment withdrawal due to adverse event compared with placebo (low certainty).

• Desmopressin for treating nocturia in men 2017 · Cochrane Headline outcomes only
  RR 3.05 [0.13, 73.39]
  1 study · 115 participants
  Low
• Desmopressin for treating nocturia in men 2017 · Cochrane Headline outcomes only
  RR 1.1 [0.56, 2.15]
  4 studies · 614 participants
  Low

Desmopressin vs alpha‐blocker

• Desmopressin for treating nocturia in men 2017 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 31 participants
  Low

Desmopressin vs behaviour modifications

The review found no eligible studies for this question.

• Desmopressin for treating nocturia in men 2017 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Desmopressin plus alpha‐blocker vs alpha‐blocker

Desmopressin plus alpha‐blocker showed no clear difference in treatment withdrawal due to adverse event compared with alpha‐blocker (low certainty).

• Desmopressin for treating nocturia in men 2017 · Cochrane Headline outcomes only
  RR 2.84 [0.46, 17.66]
  3 studies · 402 participants
  Low

Desmopressin plus alpha‐blocker vs alpha‐blocker plus anticholinergic

Desmopressin plus alpha‐blocker may leads to lower treatment withdrawal due to adverse event compared with alpha‐blocker plus anticholinergic (low certainty).

• Desmopressin for treating nocturia in men 2017 · Cochrane Headline outcomes only
  RR 0.22 [0.05, 0.98]
  1 study · 427 participants
  Low