What do systematic reviews say?

Corticosteroids vs promethazine

Corticosteroids showed no clear difference in intervention side effects: drowsiness 48hrs and 3‐10 days compared with promethazine (low certainty).

• Interventions for treating hyperemesis gravidarum 2016 · Cochrane Headline outcomes only
  RR 0.08 [0, 1.32]
  1 study · 80 participants
  Low

Corticosteroids vs placebo

It is very uncertain whether corticosteroids changes intervention side effects compared with placebo (very low certainty).

• Interventions for treating hyperemesis gravidarum 2016 · Cochrane Headline outcomes only
  RR 0.79 [0.06, 11.2]
  1 study · 25 participants
  Very low

Corticosteroids vs placebo

It is very uncertain whether corticosteroids changes vomiting ‐ intraoperative compared with placebo (very low certainty).

• Interventions for preventing nausea and vomiting in women undergoing regional anaesthesia for caesarean section 2021 · Cochrane Headline outcomes only
  RR 0.52 [0.31, 0.87]
  6 studies · 609 participants
  Very low

Corticosteroids vs placebo

Corticosteroids probably leads to lower nausea ‐ postoperative compared with placebo (moderate certainty).

• Interventions for preventing nausea and vomiting in women undergoing regional anaesthesia for caesarean section 2021 · Cochrane Headline outcomes only
  RR 0.59 [0.49, 0.73]
  6 studies · 733 participants
  Moderate
• Interventions for preventing nausea and vomiting in women undergoing regional anaesthesia for caesarean section 2021 · Cochrane Headline outcomes only
  RR 0.56 [0.37, 0.83]
  6 studies · 609 participants
  Very low

Corticosteroids vs placebo

Corticosteroids may leads to lower vomiting ‐ postoperative compared with placebo (low certainty).

• Interventions for preventing nausea and vomiting in women undergoing regional anaesthesia for caesarean section 2021 · Cochrane Headline outcomes only
  RR 0.68 [0.49, 0.95]
  7 studies · 793 participants
  Low

Corticosteroids vs promethazine

Corticosteroids may leads to higher severe nausea 48 hours compared with promethazine (low certainty).

• Interventions for treating hyperemesis gravidarum 2016 · Cochrane Headline outcomes only
  RR 2 [1.08, 3.72]
  1 study · 80 participants
  Low

Corticosteroids vs promethazine

It is very uncertain whether corticosteroids changes severe nausea 17th day compared with promethazine (very low certainty).

• Interventions for treating hyperemesis gravidarum 2016 · Cochrane Headline outcomes only
  RR 0.81 [0.58, 1.15]
  1 study · 78 participants
  Very low

Corticosteroids vs promethazine

It is very uncertain whether corticosteroids changes episodes of vomiting 48 hours compared with promethazine (very low certainty).

• Interventions for treating hyperemesis gravidarum 2016 · Cochrane Headline outcomes only
  RR 3 [0.33, 27.63]
  1 study · 80 participants
  Very low
• Interventions for treating hyperemesis gravidarum 2016 · Cochrane Headline outcomes only
  RR 1 [0.21, 4.65]
  1 study · 78 participants
  Very low

Corticosteroids vs promethazine

Corticosteroids showed no clear difference in stillbirth and neonatal death compared with promethazine (low certainty).

• Interventions for treating hyperemesis gravidarum 2016 · Cochrane Headline outcomes only
  RR 3 [0.13, 69.52]
  1 study · 40 participants
  Low

Corticosteroids vs promethazine

Corticosteroids showed no clear difference in preterm birth compared with promethazine (low certainty).

• Interventions for treating hyperemesis gravidarum 2016 · Cochrane Headline outcomes only
  RR 3 [0.13, 69.52]
  1 study · 40 participants
  Low

Corticosteroids vs promethazine

The review found no eligible studies for this question.

• Interventions for treating hyperemesis gravidarum 2016 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Corticosteroids vs placebo

• Interventions for treating hyperemesis gravidarum 2016 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 110 participants
  Very low

Corticosteroids vs placebo

It is very uncertain whether corticosteroids changes pregnancy complications compared with placebo (very low certainty).

• Interventions for treating hyperemesis gravidarum 2016 · Cochrane Headline outcomes only
  RR 0.61 [0.26, 1.47]
  1 study · 110 participants
  Very low

Corticosteroids vs placebo

It is very uncertain whether corticosteroids changes spontaneous abortion compared with placebo (very low certainty).

• Interventions for treating hyperemesis gravidarum 2016 · Cochrane Headline outcomes only
  RR 0.64 [0.11, 3.7]
  1 study · 110 participants
  Very low

Corticosteroids vs placebo

It is very uncertain whether corticosteroids changes stillbirth and neonatal death compared with placebo (very low certainty).

• Interventions for treating hyperemesis gravidarum 2016 · Cochrane Headline outcomes only
  RR 0.7 [0.15, 3.34]
  2 studies · 134 participants
  Very low

Corticosteroids vs placebo

It is very uncertain whether corticosteroids changes congenital abnormalities compared with placebo (very low certainty).

• Interventions for treating hyperemesis gravidarum 2016 · Cochrane Headline outcomes only
  RR 0.32 [0.01, 7.73]
  1 study · 110 participants
  Very low

Corticosteroids vs placebo

It is very uncertain whether corticosteroids changes preterm birth compared with placebo (very low certainty).

• Interventions for treating hyperemesis gravidarum 2016 · Cochrane Headline outcomes only
  RR 1.01 [0.31, 3.28]
  2 studies · 134 participants
  Very low

Corticosteroids vs placebo

The review found no eligible studies for this question.

• Interventions for treating hyperemesis gravidarum 2016 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found