Findings

What do systematic reviews say?

2 questions · 3 findings · 2 reviews · Airways

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 33.3%Moderate 2 · 66.7%High 0 · 0%

Intramuscular corticosteroids vs oral corticosteroid

Relapse · patients with acute asthma

Intramuscular corticosteroids showed no clear difference in relapse within 10 days post‐discharge compared with oral corticosteroids (moderate certainty).

2 findings from 1 review

Intramuscular versus oral corticosteroids to reduce relapses following discharge from the emergency department for… 2018 · Cochrane Headline outcomes only
RR 0.74 [0.51, 1.07]
7 studies · 742 participants
Moderate
Intramuscular versus oral corticosteroids to reduce relapses following discharge from the emergency department for… 2018 · Cochrane Headline outcomes only
RR 0.99 [0.74, 1.33]
5 studies · 556 participants
Low

Inhaled corticosteroids plus standard care vs placebo or usual care

Resolution of symptoms · adults with a confirmed diagnosis of mild COVID‐19, of whom only 10% (219/2132) participants had received ≥ 1 vaccination

Inhaled corticosteroids plus standard care probably leads to higher symptom resolution: all initial symptoms resolved at day 14 compared with standard care (with or without placebo) (moderate certainty).

1 finding from 1 review

Inhaled corticosteroids for the treatment of COVID‐19 2022 · Cochrane Headline outcomes only
RR 1.19 [1.09, 1.3]
2 studies · 1986 participants
Moderate