Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

404 questions · 431 findings · 55 reviews · Headline outcomes only

No studies found 64 · 14.8%GRADE not reported 14 · 3.2%Very low 99 · 23%Low 137 · 31.8%Moderate 86 · 20%High 31 · 7.2%

Corticosteroids vs no corticosteroid use

Disease‐specific mortality ‐ SJS and TEN (time to · Stevens‐Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and SJS/TEN overlap syndrome

It is very uncertain whether corticosteroids changes disease‐specific mortality ‐ SJS and TEN (time to compared with no corticosteroids (very low certainty).

1 finding from 1 review

Corticosteroids vs no corticosteroid use

Adverse effects leading to discontinuation of SJT/TEN therapy ‐ not reported · Stevens‐Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and SJS/TEN overlap syndrome

The review found no eligible studies for this question.

1 finding from 1 review