Clinical improvement: discharged alive ( · hospitalised and unvaccinated individuals with a confirmed or suspected diagnosis of symptomatic COVID‐19
Summary of findings table ‐ Corticosteroids plus standard care may leads to higher clinical improvement: discharged alive ( compared with standard care (plus/minus placebo) (low certainty).
1 finding from 1 review
Clinical worsening: new need for invasive mechanical ventilation or death · hospitalised and unvaccinated individuals with a confirmed or suspected diagnosis of symptomatic COVID‐19
Summary of findings table ‐ Corticosteroids plus standard care showed no clear difference in clinical worsening: new need for invasive mechanical ventilation or… compared with standard care (plus/minus placebo) (low certainty).
1 finding from 1 review
Serious adverse events ( · hospitalised and unvaccinated individuals with a confirmed or suspected diagnosis of symptomatic COVID‐19
1 finding from 1 review
Adverse events: all grades · hospitalised and unvaccinated individuals with a confirmed or suspected diagnosis of symptomatic COVID‐19
1 finding from 1 review
Hospital‐acquired infections ( · hospitalised and unvaccinated individuals with a confirmed or suspected diagnosis of symptomatic COVID‐19
1 finding from 1 review
Invasive fungal infection · hospitalised and unvaccinated individuals with a confirmed or suspected diagnosis of symptomatic COVID‐19
1 finding from 1 review
B3: Caesarean section – an all women · the woman
Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids showed no clear difference in B3: Caesarean section – an all women compared with single course (moderate certainty).
1 finding from 1 review
B4: Discontinuation of therapy due to maternal adverse effects – an all women · the woman
1 finding from 1 review
Admission to the intensive care unit ‐ not reported · the woman
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Breastfeeding at hospital discharge ‐ not reported · the woman
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
C1: Total deaths (after randomisation) up to early childhood · the child
Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids showed no clear difference in C1: Total deaths (after randomisation) up to early childhood compared with single course (moderate certainty).
1 finding from 1 review
C2: Neurodevelopmental impairment at early childhood · the child
Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids showed no clear difference in C2: Neurodevelopmental impairment at early childhood compared with single course (high certainty).
1 finding from 1 review
C3: Survival free of neurodevelopmental impairment at early childhood · the child
Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids showed no clear difference in C3: Survival free of neurodevelopmental impairment at early childhood compared with single course (high certainty).
1 finding from 1 review
C4: Survival free of major neurodevelopmental impairment atearly childhood · the child
Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids showed no clear difference in C4: Survival free of major neurodevelopmental impairment atearly… compared with single course (moderate certainty).
1 finding from 1 review
D1: Total deaths (after randomisation) up to mid‐ to later childhood · the child
Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids showed no clear difference in D1: Total deaths (after randomisation) up to mid‐ to later childhood compared with single course (moderate certainty).
1 finding from 1 review
D2: Neurocognitive impairment atmid‐ to later childhood · the child
Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids showed no clear difference in D2: Neurocognitive impairment atmid‐ to later childhood compared with single course (low certainty).
1 finding from 1 review
D3: Survival free of neurocognitive impairment atmid‐ to later childhood · the child
Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids showed no clear difference in D3: Survival free of neurocognitive impairment atmid‐ to later… compared with single course (moderate certainty).
1 finding from 1 review
D4: Survival free of major neurocognitive impairment atmid‐ to later childhood · the child
Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids showed no clear difference in D4: Survival free of major neurocognitive impairment atmid‐ to later… compared with single course (moderate certainty).
1 finding from 1 review
Maternal death · the woman
Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids showed no clear difference in B1: Maternal death – all women compared with single course (low certainty).
1 finding from 1 review
B2: Maternal sepsis – an all women · the woman
Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids showed no clear difference in B2: Maternal sepsis – an all women compared with single course (moderate certainty).
1 finding from 1 review