Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

415 questions · 442 findings · 58 reviews

No studies found 70 · 15.8%GRADE not reported 19 · 4.3%Very low 99 · 22.4%Low 137 · 31%Moderate 86 · 19.5%High 31 · 7%

Antivirals plus corticosteroids vs corticosteroids plus placebo or no treatment

Motor synkinesis or crocodile tears № of participants: 469 (2 RCTs) · Bell's palsy

Antivirals plus corticosteroids probably leads to lower motor synkinesis or crocodile tears № of participants: 469 (2 RCTs) compared with corticosteroids plus placebo or no treatment (AS versus OS) (moderate certainty).

1 finding from 1 review

Antivirals plus corticosteroids vs corticosteroids plus placebo or no treatment

Adverse events № of participants: 656 (2 RCTs) · Bell's palsy

It is very uncertain whether antivirals plus corticosteroids changes adverse events № of participants: 656 (2 RCTs) compared with corticosteroids plus placebo or no treatment (AS versus OS) (very low certainty).

1 finding from 1 review

Summary of findings for NSAIDs plus corticosteroids vs corticosteroids

Proportion of participants with cystoid macular edema 1 week · people who received phacoemulsification

Summary of findings for NSAIDs plus corticosteroids may leads to lower proportion of participants with cystoid macular edema 1 week compared with corticosteroids alone (low certainty).

1 finding from 1 review

Summary of findings for NSAIDs plus corticosteroids vs corticosteroids

Intraocular inflammation measured by proportion of participants with corneal edema 1 week · people who received phacoemulsification

Summary of findings for NSAIDs plus corticosteroids showed no clear difference in intraocular inflammation measured by proportion of participants with… compared with corticosteroids alone (moderate certainty).

1 finding from 1 review

Intratympanic corticosteroids vs placebo/no treatment

Improvement in vertigo frequency · Ménière’s disease

Intratympanic corticosteroids showed no clear difference in improvement in vertigo frequency compared with placebo/no treatment (low certainty).

2 findings from 1 review

Intratympanic corticosteroids vs placebo/no treatment

Change in vertigo frequency · Ménière’s disease
3 findings from 1 review

Intratympanic corticosteroids vs no treatment or versus placebo

Change in hearing threshold determined by PTA Range 0 dB to 140 dB Negative values represent lowering and positive values represent raising of the hearing threshold. A lower hearing threshold represents hearing improvement. Â · sudden sensorineural hearing loss

Intratympanic corticosteroids showed no clear difference in change in hearing threshold determined by PTA Range 0 dB to 140 dB… compared with no treatment or versus placebo (low certainty).

1 finding from 1 review

Intratympanic corticosteroids vs no treatment or versus placebo

Final hearing threshold determined by PTA (a lower value represents better hearing) · sudden sensorineural hearing loss

Intratympanic corticosteroids showed no clear difference in final hearing threshold determined by PTA (a lower value represents… compared with no treatment or versus placebo (low certainty).

1 finding from 1 review