Findings

What do systematic reviews say?

6 questions · 7 findings · 1 reviews · Neonatal

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No studies found 5 · 71.4%GRADE not reported 0 · 0%Very low 2 · 28.6%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Continuous infusion vs bolus administration

Pain · postoperative pain in neonates

It is very uncertain whether continuous infusion changes pain compared with bolus administration (very low certainty).

2 findings from 1 review

Systemic opioid regimens for postoperative pain in neonates 2023 · Cochrane Headline outcomes only
MD 0
2 studies · 133 participants
Very low
Systemic opioid regimens for postoperative pain in neonates 2023 · Cochrane Headline outcomes only
MD 0.07
2 studies · 133 participants
Very low

Continuous infusion vs bolus administration

All‐cause mortality during initial hospitalization ‐ not reported · postoperative pain in neonates

The review found no eligible studies for this question.

1 finding from 1 review

Systemic opioid regimens for postoperative pain in neonates 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Continuous infusion vs bolus administration

Major neurodevelopmental disability in children aged 18 to 24 months or three to five years old ‐ not reported · postoperative pain in neonates

The review found no eligible studies for this question.

1 finding from 1 review

Systemic opioid regimens for postoperative pain in neonates 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Continuous infusion vs bolus administration

Cognitive and educational outcomes in children more than five years old ‐ not reported · postoperative pain in neonates

The review found no eligible studies for this question.

1 finding from 1 review

Systemic opioid regimens for postoperative pain in neonates 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Continuous infusion vs bolus administration

Severe (defined as stage 3 or greater) retinopathy of prematurity ‐ not reported · postoperative pain in neonates

The review found no eligible studies for this question.

1 finding from 1 review

Systemic opioid regimens for postoperative pain in neonates 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Continuous infusion vs bolus administration

Severe (grade 3 or greater) intraventricular hemorrhage (IVH) on cranial ultrasound ‐ not reported · postoperative pain in neonates

The review found no eligible studies for this question.

1 finding from 1 review

Systemic opioid regimens for postoperative pain in neonates 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found