Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

258 questions · 263 findings · 32 reviews

No studies found 75 · 28.5%GRADE not reported 30 · 11.4%Very low 58 · 22.1%Low 61 · 23.2%Moderate 31 · 11.8%High 8 · 3%

Continuous platinum infusion vs bolus platinum infusion

Hearing loss · children with cancer treated with platinum‐based therapy

Continuous platinum infusion showed no clear difference in hearing loss (asymptomatic and symptomatic disease according to… compared with bolus platinum infusion (low certainty).

1 finding from 1 review

Continuous platinum infusion vs bolus platinum infusion

Adverse effects: toxic death (no definition provided) · children with cancer treated with platinum‐based therapy

Continuous platinum infusion showed no clear difference in adverse effects: toxic death (no definition provided) compared with bolus platinum infusion (low certainty).

1 finding from 1 review