Findings

What do systematic reviews say?

4 questions · 8 findings · 1 reviews · Headline outcomes only

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 3 · 37.5%Moderate 5 · 62.5%High 0 · 0%

Combined oral contraceptive pill vs no pretreatment

Live birth or ongoing pregnancy · women undergoing assisted reproduction

Combined oral contraceptive pill probably leads to lower live birth or ongoing pregnancy (COCP + Ant vs Ant) compared with no pretreatment (moderate certainty).

2 findings from 1 review

Oral contraceptive pill, progestogen or oestrogen pretreatment for ovarian stimulation protocols for women undergoing… 2017 · Cochrane Headline outcomes only
OR 0.74 [0.58, 0.95]
6 studies · 1335 participants
Moderate
Oral contraceptive pill, progestogen or oestrogen pretreatment for ovarian stimulation protocols for women undergoing… 2017 · Cochrane Headline outcomes only
OR 0.89 [0.64, 1.25]
4 studies · 724 participants
Moderate

Combined oral contraceptive pill vs no pretreatment

Pregnancy loss · women undergoing assisted reproduction

Combined oral contraceptive pill showed no clear difference in pregnancy loss (COCP + Ant vs Ant) compared with no pretreatment (moderate certainty).

2 findings from 1 review

Oral contraceptive pill, progestogen or oestrogen pretreatment for ovarian stimulation protocols for women undergoing… 2017 · Cochrane Headline outcomes only
OR 1.36 [0.82, 2.26]
5 studies · 868 participants
Moderate
Oral contraceptive pill, progestogen or oestrogen pretreatment for ovarian stimulation protocols for women undergoing… 2017 · Cochrane Headline outcomes only
OR 0.4 [0.22, 0.72]
5 studies · 780 participants
Moderate

Combined oral contraceptive pill vs no pretreatment

Multiple pregnancy rate · women undergoing assisted reproduction

Combined oral contraceptive pill showed no clear difference in multiple pregnancy rate (COCP + Ant vs Ant) compared with no pretreatment (low certainty).

2 findings from 1 review

Oral contraceptive pill, progestogen or oestrogen pretreatment for ovarian stimulation protocols for women undergoing… 2017 · Cochrane Headline outcomes only
OR 2.21 [0.53, 9.26]
2 studies · 125 participants
Low
Oral contraceptive pill, progestogen or oestrogen pretreatment for ovarian stimulation protocols for women undergoing… 2017 · Cochrane Headline outcomes only
OR 1.36 [0.85, 2.19]
4 studies · 546 participants
Moderate

Combined oral contraceptive pill vs no pretreatment

OHSS · women undergoing assisted reproduction

Combined oral contraceptive pill showed no clear difference in OHSS rate (COCP + Ant vs Ant) compared with no pretreatment (low certainty).

2 findings from 1 review

Oral contraceptive pill, progestogen or oestrogen pretreatment for ovarian stimulation protocols for women undergoing… 2017 · Cochrane Headline outcomes only
OR 0.98 [0.28, 3.4]
2 studies · 642 participants
Low
Oral contraceptive pill, progestogen or oestrogen pretreatment for ovarian stimulation protocols for women undergoing… 2017 · Cochrane Headline outcomes only
OR 0.63 [0.2, 1.96]
2 studies · 290 participants
Low